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MBTD1 Knockout Cell Lines

Gene: MBTD1

Official Full Name: mbt domain containing 1provided by HGNC

Gene Summary: Enables NuA4 histone acetyltransferase complex binding activity and methylated histone binding activity. Involved in double-strand break repair via homologous recombination; positive regulation of double-strand break repair via homologous recombination; and regulation of cell cycle. Part of NuA4 histone acetyltransferase complex and nucleosome. Is active in site of double-strand break. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO20360 MBTD1 Knockout cell line (HeLa) Human MBTD1 1:3~1:6 Negative Online Inquiry
KO20361 MBTD1 Knockout cell line (HCT 116) Human MBTD1 1:2~1:4 Negative Online Inquiry
KO20362 MBTD1 Knockout cell line (HEK293) Human MBTD1 1:3~1:6 Negative Online Inquiry
KO20363 MBTD1 Knockout cell line (A549) Human MBTD1 1:3~1:4 Negative Online Inquiry

Background

MBTD1 Gene Knockout Cell Lines are specialized cellular models engineered to lack the expression of the MBTD1 gene, a gene implicated in critical cellular processes such as gene regulation, chromatin remodeling, and cellular signaling pathways. Through CRISPR-Cas9 technology, these cell lines permit precise editing, resulting in the complete knockout of MBTD1. The loss of this gene allows researchers to elucidate its specific roles in cellular function and disease mechanisms, especially in cancer biology and developmental studies.

The primary function of the MBTD1 Gene Knockout Cell Lines lies in their capacity to serve as a powerful tool for functional genomics. By investigating how cellular processes are altered in the absence of MBTD1, researchers can gain insights into the gene's contribution to various pathophysiological conditions, including tumorigenesis and metabolic disorders. These cell lines enable the exploration of potential therapeutic targets and biomarkers, paving the way for novel treatment strategies.

Scientifically, the applications of MBTD1 Gene Knockout Cell Lines are vast. They can be used in studies focusing on epigenetic regulation, differentiation protocols, and cellular response to stressors. In clinical settings, understanding the role of MBTD1 can facilitate improved patient stratification and personalized medicine approaches.

What sets our MBTD1 Gene Knockout Cell Lines apart is the meticulous validation process they undergo, ensuring consistency and reproducibility of experimental outcomes, which are often significant challenges in biological research. Coupled with our user-friendly protocols and technical support, these cell lines provide unique advantages over generic knockouts regarding specificity and application scope.

For researchers and clinicians aiming to advance their understanding of gene function and its implications in health and disease, the MBTD1 Gene Knockout Cell Lines are an invaluable asset. Our company combines industry-leading expertise in genetic engineering with a commitment to quality, ensuring that our products meet the highest standards for scientific rigor and reliability. Whether you are conducting basic research or developing clinical applications, our products are designed to support your research objectives effectively.

Please note that all services are for research use only. Not intended for any clinical use.

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