Gene: LRRC27
Official Full Name: leucine rich repeat containing 27provided by HGNC
Gene Summary: Predicted to enable actin binding activity. Predicted to be involved in cardiac muscle cell development. Predicted to be active in cytoskeleton and sarcomere. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO26023 | LRRC27 Knockout cell line (HeLa) | Human | LRRC27 | 1:3~1:6 | Negative | Online Inquiry |
KO26024 | LRRC27 Knockout cell line (HCT 116) | Human | LRRC27 | 1:2~1:4 | Negative | Online Inquiry |
KO26025 | LRRC27 Knockout cell line (HEK293) | Human | LRRC27 | 1:3~1:6 | Negative | Online Inquiry |
KO26026 | LRRC27 Knockout cell line (A549) | Human | LRRC27 | 1:3~1:4 | Negative | Online Inquiry |
LRRC27 Gene Knockout Cell Lines are engineered cellular models that specifically lack the expression of the LRRC27 gene, which has been implicated in various cellular processes, including adhesion, proliferation, and apoptotic regulation. These knockout cell lines are created using advanced CRISPR-Cas9 gene-editing technology, allowing precise modifications at the genomic level. By disabling the LRRC27 gene, researchers can gain insights into its function and the molecular pathways it influences, providing a powerful tool for studying gene function and regulation in cellular contexts.
The primary function of the LRRC27 gene knockout cell lines lies in their utility for elucidating the role of LRRC27 in cancer biology, developmental processes, and the cellular response to stresses. By comparing the knockout lines with their wild-type counterparts, researchers can detect variations in cell morphology, signaling cascades, and overall physiological responses, which can inform drug development and therapeutic strategies.
In both research and clinical settings, these cell lines serve as invaluable resources for investigating the molecular underpinnings of diseases, specifically those where LRRC27 is suspected to act as a contributor. By providing a clearer understanding of LRRC27's biological roles, these models facilitate the identification of potential drug targets and biomarkers.
One of the key advantages of using LRRC27 Knockout Cell Lines is their specificity and reproducibility. Compared to other methods, such as RNA interference, which can lead to off-target effects, the complete knockout of the gene ensures that observed phenotypic changes can be directly attributed to the lack of LRRC27 expression. Moreover, these cell lines are compatible with a range of assays, including viability tests, migration assays, and gene expression analyses, enhancing their versatility.
Researchers and clinicians will find immense value in LRRC27 Gene Knockout Cell Lines as they represent a cutting-edge approach to gene function studies, promising enhanced accuracy and reliability in experimental outcomes. The ability to observe the full impact of removing the LRRC27 gene grants a deeper understanding of its role in health and disease.
Our company specializes in the development and optimization of gene-modified cell lines, ensuring high-quality, reproducible products tailored to meet the needs of today's biomedical research community. With our expertise, we are committed to delivering innovative solutions that advance scientific discovery and clinical applications.
Please note that all services are for research use only. Not intended for any clinical use.
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