Gene: LRRC14
Official Full Name: leucine rich repeat containing 14provided by HGNC
Gene Summary: This gene encodes a leucine-rich repeat-containing protein. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO32927 | LRRC14 Knockout cell line (HeLa) | Human | LRRC14 | 1:3~1:6 | Negative | Online Inquiry |
KO32928 | LRRC14 Knockout cell line (HCT 116) | Human | LRRC14 | 1:2~1:4 | Negative | Online Inquiry |
KO32929 | LRRC14 Knockout cell line (HEK293) | Human | LRRC14 | 1:3~1:6 | Negative | Online Inquiry |
KO32930 | LRRC14 Knockout cell line (A549) | Human | LRRC14 | 1:3~1:4 | Negative | Online Inquiry |
LRRC14 Gene Knockout Cell Lines are genetically engineered cellular models designed to facilitate functional studies of the LRRC14 gene, a member of the leucine-rich repeat-containing family of proteins. These cell lines serve as a powerful tool for researchers aiming to elucidate the biological role of LRRC14 in various cellular processes, including signaling pathways, cellular proliferation, and differentiation. The knockout of the LRRC14 gene is achieved through advanced CRISPR-Cas9 technology, ensuring precise disruption of its coding sequence, which allows for the assessment of downstream effects on cellular functionality and behavior.
The primary mechanism behind the utility of these knockout cell lines lies in their ability to provide insights into the specific contributions of LRRC14. This facilitates the exploration of its involvement in vital physiological processes and potential pathophysiological implications, such as its role in cancer progression or immune responses. Thus, these models are invaluable for basic research and offer promising applications in drug discovery, therapeutic developments, and understanding disease mechanisms.
Compared to conventional cell lines, our LRRC14 Knockout Cell Lines offer distinct advantages, including reduced off-target effects and enhanced reproducibility of experimental results. Additionally, the specificity of the gene knockout allows for clearer characterization of LRRC14’s functions without the confounding effects of its expression. Researchers and clinicians will appreciate the rigorous validation provided for these lines, which ensures results are both reliable and translatable to real-world applications.
Our commitment to supporting scientific advancement is reflected in the quality of our products. With a strong foundation in genetic engineering and molecular biology, we are dedicated to providing cutting-edge tools that empower researchers and clinicians alike in their pursuit of new knowledge and therapies. By choosing our LRRC14 Gene Knockout Cell Lines, users are assured of a resource that enhances experimentation and expands the possibilities within biological research.
Please note that all services are for research use only. Not intended for any clinical use.
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