Gene: LRIG3
Official Full Name: leucine rich repeats and immunoglobulin like domains 3provided by HGNC
Gene Summary: Predicted to act upstream of or within otolith morphogenesis. Located in extracellular space. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO29712 | LRIG3 Knockout cell line (HeLa) | Human | LRIG3 | 1:3~1:6 | Negative | Online Inquiry |
KO29713 | LRIG3 Knockout cell line (HCT 116) | Human | LRIG3 | 1:2~1:4 | Negative | Online Inquiry |
KO29714 | LRIG3 Knockout cell line (HEK293) | Human | LRIG3 | 1:3~1:6 | Negative | Online Inquiry |
KO29715 | LRIG3 Knockout cell line (A549) | Human | LRIG3 | 1:3~1:4 | Negative | Online Inquiry |
LRIG3 Gene Knockout Cell Lines are specialized cellular models that have been engineered to lack the expression of the Leucine-Rich Repeat and Immunoglobulin-Like Domains 3 (LRIG3) gene. These cell lines serve as invaluable tools in molecular biology and genetic research, particularly in the study of signal transduction, cell proliferation, and oncogenesis. The knockout of LRIG3, which plays a critical role in regulating receptor tyrosine kinases and mitigating growth factor signaling, allows researchers to investigate the biological consequences of its absence, thereby elucidating its involvement in various pathological conditions, including cancer.
The primary function of these cell lines hinges on their capacity to mimic disease-specific environments, facilitating the examination of cellular behaviors in response to external stimuli. By providing insights into the LRIG3-mediated regulatory mechanisms, researchers can better understand how aberrant signaling pathways contribute to tumorigenesis and identify potential therapeutic targets. Moreover, the use of LRIG3 knockout models can expedite the discovery of novel treatment strategies by enabling high-throughput screening of pharmacological agents in a controlled setting.
In comparison to other gene knockout models, the LRIG3 knockout cell lines offer the unique advantage of being readily accessible and easy to manipulate. Each cell line is thoroughly characterized to ensure consistency and reliability, enabling reproducibility across experiments, which is crucial for advancing both fundamental and translational research. Additionally, these cell lines are produced under strict quality assurance protocols to guarantee their validity and functionality, distinguishing them from alternatives that may lack rigorous validation.
For researchers and clinicians dedicated to advancing our understanding of complex cellular mechanisms and developing targeted therapies, LRIG3 Gene Knockout Cell Lines represent an essential resource. Their capacity to elucidate the role of LRIG3 in human health and disease makes them a critical asset for innovative research. Our company prides itself on its expertise in generating high-quality biological products, ensuring that you receive tools that are not only scientifically robust but tailored to meet the evolving demands of the research community.
Please note that all services are for research use only. Not intended for any clinical use.
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