Gene: LONRF3
Official Full Name: LON peptidase N-terminal domain and ring finger 3provided by HGNC
Gene Summary: The protein encoded by this gene contains a RING finger domain, a motif present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions. Multiple alternatively spliced transcript variants have been suggested, but their full length natures are not clear. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO16505 | LONRF3 Knockout cell line (HeLa) | Human | LONRF3 | 1:3~1:6 | Negative | Online Inquiry |
KO16506 | LONRF3 Knockout cell line (HCT 116) | Human | LONRF3 | 1:2~1:4 | Negative | Online Inquiry |
KO16507 | LONRF3 Knockout cell line (HEK293) | Human | LONRF3 | 1:3~1:6 | Negative | Online Inquiry |
KO16508 | LONRF3 Knockout cell line (A549) | Human | LONRF3 | 1:3~1:4 | Negative | Online Inquiry |
LONRF3 Gene Knockout Cell Lines are specifically engineered cellular models that facilitate the study of the LONRF3 gene's role in various biological processes. By utilizing a robust CRISPR/Cas9 genetic editing technology, these cell lines provide researchers with the ability to explore the functional consequences of gene knockout and its downstream effects on cellular pathways. The targeted disruption of LONRF3 allows for in-depth analyses of its involvement in cellular stress responses, metabolic regulation, and potential implications in disease states, particularly in cancer pathology.
The primary mechanism at play involves the CRISPR/Cas9 system, which introduces specific double-strand breaks in the genomic DNA, leading to frameshifts or deletions that render the LONRF3 gene nonfunctional. This targeted approach significantly enhances the reliability of research findings, offering clear insights into gene function devoid of confounding variations often present in wild-type models.
LONRF3 Gene Knockout Cell Lines hold significant scientific importance, particularly in advancing our understanding of therapeutic targets in oncology and metabolic disorders. They enable researchers to systematically evaluate how the loss of LONRF3 alters cellular behavior, making it a valuable tool for drug discovery and pathway elucidation. Because of their versatility, these cell lines can be utilized across various research settings, from basic biology to translational medicine.
One of the unique selling points of our LONRF3 Gene Knockout Cell Lines is their high fidelity and reproducibility compared to alternative models, such as transient transfection methods or more conventional knockdown approaches. Users can achieve reliable and consistent results, enhancing the robustness of experimental outcomes while minimizing the variability associated with non-targeted interventions.
For researchers and clinicians alike, the value of LONRF3 Gene Knockout Cell Lines lies not only in their cutting-edge design but also in the potential to unlock novel biological discoveries. As these insights translate into therapeutic strategies, the ability to target specific genetic alterations holds promise for the development of more effective treatments.
Our company's expertise in genetic engineering and commitment to quality ensure that each cell line is rigorously validated for performance and specificity, empowering researchers with tools that push the boundaries of biological understanding. With LONRF3 Gene Knockout Cell Lines, users can confidently advance their research while contributing to the broader scientific community.
Please note that all services are for research use only. Not intended for any clinical use.
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