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LMTK3 Knockout Cell Lines

Gene: LMTK3

Official Full Name: lemur tyrosine kinase 3provided by HGNC

Gene Summary: Predicted to enable protein kinase activity. Predicted to be involved in chromatin remodeling. Predicted to be located in Golgi membrane; axon; and dendrite. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO30771 LMTK3 Knockout cell line (HCT 116) Human LMTK3 1:2~1:4 Negative Online Inquiry
KO30772 LMTK3 Knockout cell line (HEK293) Human LMTK3 1:3~1:6 Negative Online Inquiry
KO30773 LMTK3 Knockout cell line (A549) Human LMTK3 1:3~1:4 Negative Online Inquiry

Background

LMTK3 Gene Knockout Cell Lines consist of highly specialized cellular models that have been genetically engineered to lack the expression of the LMTK3 (Lemur Tyrosine Kinase 3) gene. This gene is implicated in various cellular processes, including cell signaling, proliferation, and response to external stimuli. By employing CRISPR-Cas9 gene editing or other knockout techniques, these cell lines allow researchers to study the functional consequences of LMTK3 loss, helping to elucidate the pathways and mechanisms influenced by this kinase.

The primary function of LMTK3 involves its role in regulating essential signaling cascades, particularly those associated with oncogenesis and cellular stress response. Lack of LMTK3 activity can alter growth patterns, apoptosis, and differentiation, making these knockout cell lines invaluable for investigations into cancer biology, neurodegenerative diseases, and metabolic disorders. Researchers can leverage these models to dissect the molecular mechanisms underlying disease progression and to identify potential therapeutic targets.

The scientific importance of LMTK3 Gene Knockout Cell Lines extends to both basic and applied research. In clinical settings, they hold the potential to contribute to the development of targeted therapies, as they provide insights into the therapeutic relevance of LMTK3 inhibition. In contrast to conventional cell lines, knockout models simulate genetic conditions more accurately, offering more biologically relevant data that can support the development of preclinical studies and drug discovery.

One key advantage of LMTK3 Gene Knockout Cell Lines is their specificity and reliability. Compared to alternative methods, such as siRNA knockdown, gene knockout provides a more permanent and stable system for studying gene functions, thereby yielding clearer results. These cell lines are rigorously validated for successful gene editing, ensuring that researchers can achieve reproducibility and reliability in their experimental setups.

For researchers, clinicians, and pharmaceutical developers, LMTK3 Gene Knockout Cell Lines present a unique opportunity to advance their studies into LMTK3-related pathways, with the dual benefits of supporting fundamental research and informing translational applications. The comprehensive data generated from these models can facilitate the design of innovative therapeutics and enhance our understanding of LMTK3's implications in human health.

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Please note that all services are for research use only. Not intended for any clinical use.

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