Gene: LINS1
Official Full Name: lines homolog 1provided by HGNC
Gene Summary: The Drosophila segment polarity gene lin encodes a protein, lines, which plays important roles in development of the epidermis and hindgut. This gene encodes a protein containing a lines-like domain. This gene is located on chromosome 15 and clustered with the gene encoding ankyrin repeat and SOCS box-containing protein 7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2017]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO16530 | LINS1 Knockout cell line (HeLa) | Human | LINS1 | 1:3~1:6 | Negative | Online Inquiry |
KO16531 | LINS1 Knockout cell line (HCT 116) | Human | LINS1 | 1:2~1:4 | Negative | Online Inquiry |
KO16532 | LINS1 Knockout cell line (HEK293) | Human | LINS1 | 1:3~1:6 | Negative | Online Inquiry |
KO16533 | LINS1 Knockout cell line (A549) | Human | LINS1 | 1:3~1:4 | Negative | Online Inquiry |
LINS1 Gene Knockout Cell Lines are specially developed human cell lines in which the LINS1 gene, associated with critical processes in cellular differentiation and proliferation, has been inactivated. These cellular models enable researchers to investigate the phenotypic consequences of LINS1 loss and provide insights into its functional roles in various biological contexts, particularly in oncogenesis and developmental biology.
The primary function of the LINS1 Gene Knockout Cell Lines revolves around their ability to mimic the effects of LINS1 gene disruption in a controlled setting. By employing CRISPR-Cas9 or other gene-editing technologies, these cell lines exhibit precise and specific alterations in the LINS1 gene, allowing for detailed examination of cellular pathways and signaling mechanisms affected by its absence. Researchers can observe changes in cellular morphology, growth patterns, and gene expression profiles, facilitating deeper investigations into the gene's involvement in pathology.
Scientifically, these knockout cell lines are invaluable tools for research in gene function, disease modeling, and therapeutic development. They serve as essential models for studying various diseases, including cancers where LINS1 may play a role in tumor progression. By providing accurate in vitro systems that can recapitulate the effects of gene loss, these cell lines are integral to drug discovery and the validation of potential therapeutic targets.
Compared to other gene knockout systems, our LINS1 Gene Knockout Cell Lines offer enhanced specificity and efficiency, along with comprehensive validation studies that confirm the accuracy of the knockout. Additionally, their robust performance in standard laboratory assays makes them an appealing choice for researchers facing stringent time and resource constraints. The development of these cell lines is backed by extensive research and characterizations, ensuring reliability and consistency.
Researchers and clinicians will find these cell lines to be a valuable asset in unraveling the complexities of gene function and disease mechanisms. By offering reliable models that anticipate the challenges of biological research, LINS1 Gene Knockout Cell Lines empower studies that can lead to a better understanding of cellular biology and innovative therapeutic solutions. Our company prides itself on extensive expertise in the development of cutting-edge biological products, ensuring that our offerings meet the highest scientific standards to advance research and clinical applications.
Please note that all services are for research use only. Not intended for any clinical use.
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