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LIN7B Knockout Cell Lines

Gene: LIN7B

Official Full Name: lin-7 homolog B, crumbs cell polarity complex componentprovided by HGNC

Gene Summary: Enables protein domain specific binding activity. Predicted to be involved in neurotransmitter secretion; regulation of synaptic assembly at neuromuscular junction; and synaptic vesicle transport. Predicted to be located in plasma membrane. Predicted to be part of MPP7-DLG1-LIN7 complex. Predicted to be active in basolateral plasma membrane; cell-cell junction; and postsynaptic density, intracellular component. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO16542 LIN7B Knockout cell line (HeLa) Human LIN7B 1:3~1:6 Negative Online Inquiry
KO16543 LIN7B Knockout cell line (HCT 116) Human LIN7B 1:2~1:4 Negative Online Inquiry
KO16544 LIN7B Knockout cell line (HEK293) Human LIN7B 1:3~1:6 Negative Online Inquiry
KO16545 LIN7B Knockout cell line (A549) Human LIN7B 1:3~1:4 Negative Online Inquiry

Background

LIN7B Gene Knockout Cell Lines represent a innovative tool designed for investigating the role of the LIN7B gene in cellular processes. These specially engineered cell lines have undergone precise genome editing to disrupt the LIN7B gene, allowing researchers to explore its function and involvement in various biological pathways. The LIN7B gene is known for its role in synaptic formation and intracellular signaling, making these knockout cell lines invaluable for studying neurological disorders and synaptic function.

The primary mechanism through which LIN7B knockout cell lines operate is the absence of LIN7B protein, which affects the localization and stability of other protein complexes involved in cell signaling and adhesion. Researchers can utilize these cell lines to perform functional assays, analyze cellular behavior, and investigate signaling cascades in both in vitro and in vivo models. By manipulating the expression of LIN7B, scientists gain insight into its role in diseases such as schizophrenia, autism spectrum disorders, and other neurological conditions.

In scientific research and clinical applications, these cell lines offer a significant advantage over traditional models that do not provide the same level of specificity. By enabling targeted studies on the effects of LIN7B loss, researchers can focus on precise phenotypic outcomes associated with gene knockout, enhancing our understanding of disease mechanisms. Compared to alternatives that may use less specific or less effective knockout techniques, LIN7B Gene Knockout Cell Lines offer a dependable and reproducible resource for advancing scientific knowledge.

The value of LIN7B Gene Knockout Cell Lines to researchers and clinicians is clear; they provide a robust platform to test hypotheses related to LIN7B function, including potential therapeutic targets. As a product of our expertise in gene editing technology and cell line development, we are committed to delivering high-quality tools that empower researchers to drive innovative discoveries in molecular and cellular biology. By choosing our LIN7B Gene Knockout Cell Lines, users align with a leader in the field, dedicated to advancing research with precision and reliability.

Please note that all services are for research use only. Not intended for any clinical use.

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