Gene: LGALS9
Official Full Name: galectin 9provided by HGNC
Gene Summary: The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. The protein encoded by this gene is an S-type lectin. It is overexpressed in Hodgkin's disease tissue and might participate in the interaction between the H&RS cells with their surrounding cells and might thus play a role in the pathogenesis of this disease and/or its associated immunodeficiency. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO36840 | LGALS9 Knockout cell line (HeLa) | Human | LGALS9 | 1:3~1:6 | Negative | Online Inquiry |
KO36841 | LGALS9 Knockout cell line (HCT 116) | Human | LGALS9 | 1:2~1:4 | Negative | Online Inquiry |
KO36842 | LGALS9 Knockout cell line (HEK293) | Human | LGALS9 | 1:3~1:6 | Negative | Online Inquiry |
KO36843 | LGALS9 Knockout cell line (A549) | Human | LGALS9 | 1:3~1:4 | Negative | Online Inquiry |
LGALS9 Gene Knockout Cell Lines are genetically modified cell lines in which the LGALS9 (Galectin-9) gene has been disrupted, leading to the loss of its protein product. Galectin-9 is a crucial member of the galectin family of carbohydrate-binding proteins, involved in various cellular processes, such as cell adhesion, immune regulation, and apoptosis. The knockout of this gene enables researchers to investigate the functional roles of Galectin-9 in pathophysiological conditions, including cancer, autoimmune disorders, and infectious diseases.
These cell lines function by providing a controlled environment where the absence of Galectin-9 can be studied, allowing for detailed exploration of its signaling pathways and interactions with other cellular components. By utilizing these knockout models, scientists can assess how the lack of Galectin-9 influences cell behavior, immune responses, and tumorigenesis, thereby shedding light on therapeutic targets and mechanisms of diseases.
The scientific importance of LGALS9 Gene Knockout Cell Lines lies in their ability to advance our understanding of galectins in health and disease. In clinical research settings, these cell lines can serve as tools for drug discovery, enabling high-throughput screenings for potential inhibitors or modulators of biological pathways influenced by Galectin-9. Furthermore, their application in preclinical studies allows for the validation of hypotheses related to immune evasion and metastasis in cancer research.
Compared to traditional cell lines or gene editing approaches, our LGALS9 Gene Knockout Cell Lines offer unique advantages such as high specificity and reproducibility. The use of advanced genome editing technologies, such as CRISPR-Cas9, ensures precise gene disruption, leading to more reliable experimental outcomes. Researchers can save valuable time and resources, as these cell lines are ready-to-use and extensively characterized.
For researchers and clinicians focused on understanding the intricate role of Galectin-9 in various biological contexts, these knockout cell lines represent a significant value. They not only provide a deeper insight into the molecular mechanisms of diseases but also hold potential for the development of novel therapeutic interventions.
Our company prides itself on its dedication to delivering high-quality biological products that empower scientific discovery. With an established track record in the field of molecular biology and genetics, we are committed to supporting researchers in their quest for innovative solutions through our advanced offerings, including LGALS9 Gene Knockout Cell Lines.
Please note that all services are for research use only. Not intended for any clinical use.
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