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LCTL Knockout Cell Lines

Gene: LCTL

Official Full Name: lactase likeprovided by HGNC

Gene Summary: This gene encodes a member of family 1 glycosidases. Glycosidases are enzymes that hydrolyze glycosidic bonds and are classified into families based on primary amino acid sequence. Most members of family 1 have two conserved glutamic acid residues, which are required for enzymatic activity. The mouse ortholog of this protein has been characterized and has a domain structure of an N-terminal signal peptide, glycosidase domain, transmembrane domain, and a short cytoplasmic tail. It lacks one of the conserved glutamic acid residues important for catalysis, and its function remains to be determined (PMID: 12084582). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO21424 LCTL Knockout cell line (HeLa) Human LCTL 1:3~1:6 Negative Online Inquiry
KO21425 LCTL Knockout cell line (A549) Human LCTL 1:3~1:4 Negative Online Inquiry

Background

LCTL Gene Knockout Cell Lines are specialized cellular models engineered to lack the expression of the LCTL (Lectin, C-Type, and Type 2) gene. This gene plays a critical role in various biological processes, including cellular adhesion, pathogen recognition, and immune response. By specifically knocking out the LCTL gene, researchers can investigate the functional implications of this gene on cell behavior, signaling pathways, and overall cellular physiology. The mechanism underlying these knockout cell lines typically involves CRISPR-Cas9 technology, allowing precise alterations to the genomic DNA, leading to a complete loss of functional LCTL protein.

Scientific research has identified numerous applications for LCTL Gene Knockout Cell Lines, particularly in the fields of immunology, cancer biology, and infection studies. For instance, these cell lines can provide insight into how the LCTL gene influences susceptibility to infections or aids in the development of cancerous characteristics, which can be pivotal for therapeutic advancements. By studying these unique cell models, researchers can elucidate underlying mechanisms that are often masked in native cellular environments, thereby contributing to the knowledge required for drug development and disease understanding.

What sets our LCTL Gene Knockout Cell Lines apart from other knockout models is their validated genetic modification, which ensures a high degree of specificity and reproducibility in experiments. Unlike other traditional models, these lines also offer a rapid turnaround time, enabling researchers to focus on their investigations without the lengthy process typically associated with generating knockout models.

The value of these cell lines is accentuated by their ability to facilitate discoveries that lead to innovative therapeutic strategies, making them an essential tool for academic and clinical researchers alike. Our commitment to quality and precision in product development underscores our expertise in providing cutting-edge tools for the scientific community, ensuring that our users have access to the best resources to advance their research goals.

Please note that all services are for research use only. Not intended for any clinical use.

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