Gene: LARP1
Official Full Name: La ribonucleoprotein 1, translational regulatorprovided by HGNC
Gene Summary: Enables eukaryotic initiation factor 4E binding activity; nucleic acid binding activity; and ribosomal small subunit binding activity. Involved in several processes, including TORC1 signaling; cellular response to rapamycin; and post-transcriptional regulation of gene expression. Located in TORC1 complex and cytoplasmic stress granule. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO05894 | LARP1 Knockout cell line (HeLa) | Human | LARP1 | 1:3~1:6 | Negative | Online Inquiry |
KO05895 | LARP1 Knockout cell line (HCT 116) | Human | LARP1 | 1:2~1:4 | Negative | Online Inquiry |
KO05896 | LARP1 Knockout cell line (HEK293) | Human | LARP1 | 1:3~1:6 | Negative | Online Inquiry |
LARP1 Gene Knockout Cell Lines are meticulously engineered cellular models designed to facilitate in-depth research on the LARP1 gene and its implications in cellular regulation and disease pathology. By employing CRISPR/Cas9 technology, these cell lines exhibit a complete knockout of LARP1, thereby enabling researchers to elucidate its role in mRNA translation, ribosomal function, and cell proliferation. The loss of LARP1 has been shown to impact cellular responses to stress and modulation of the cell cycle, making these knockout lines critical for examining broader biological pathways.
The primary function of LARP1 involves the binding of specific RNA sequences, exerting control over protein synthesis and stability. In clinical and research settings, understanding these mechanisms can lead to insights into conditions such as cancer, where dysregulation of translation is prevalent. These cell lines can serve as valuable tools for investigating therapeutic targets and the molecular underpinnings of diseases characterized by aberrant protein synthesis.
One distinct advantage of LARP1 Gene Knockout Cell Lines is their genetic purity and reliability, which surpass alternatives that might involve incomplete knockdown or off-target effects commonly seen with RNA interference methods. Their robustness allows for reproducible experiments, thereby enhancing the validity of research findings. Additionally, researchers benefit from the convenience of having a standardized model for comparative studies across different experimental setups.
The value of LARP1 Gene Knockout Cell Lines to researchers, clinicians, and biopharmaceutical companies cannot be overstated; they provide an unprecedented opportunity to explore translational science and develop potential interventions against diseases driven by LARP1-related pathways. Our company prides itself on cutting-edge biotechnological advancements and extensive expertise in cellular model development, delivering high-quality biological products that underpin innovative research in the life sciences.
Please note that all services are for research use only. Not intended for any clinical use.
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