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KRT15 Knockout Cell Lines

Gene: KRT15

Official Full Name: keratin 15provided by HGNC

Gene Summary: The protein encoded by this gene is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains and are clustered in a region on chromosome 17q21.2. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO36871 KRT15 Knockout cell line (HeLa) Human KRT15 1:3~1:6 Negative Online Inquiry
KO36872 KRT15 Knockout cell line (HCT 116) Human KRT15 1:2~1:4 Negative Online Inquiry
KO36873 KRT15 Knockout cell line (A549) Human KRT15 1:3~1:4 Negative Online Inquiry

Background

KRT15 Gene Knockout Cell Lines are genetically engineered cell lines that enable researchers to explore the functional role of the KRT15 gene, which encodes keratin 15, a crucial protein in epithelial cells, particularly in the skin and hair follicles. By silencing the KRT15 gene through targeted knockout techniques, these cell lines provide a powerful platform for studying keratinocyte biology, wound healing, and cancer research.

The key function of KRT15 Gene Knockout Cell Lines lies in their ability to elucidate the pathways influenced by keratin 15 and its interactions with other cellular proteins and signaling networks. By observing cellular responses in the absence of KRT15, researchers can gain insights into the protein's role in epithelial development, structural integrity, and potential implications in diseases such as basal cell carcinoma and other skin disorders. This mechanistic understanding is crucial in translational research aimed at developing targeted therapies or advancing regenerative medicine strategies.

Scientifically, these knockout cell lines have far-reaching applications in both academic and clinical research. They serve as vital tools for drug screening, biomarker identification, and genetic studies, paving the way for new discoveries in cell biology and therapeutic interventions. In comparison to traditional cell lines, KRT15 Gene Knockout Cell Lines offer unparalleled specificity in gene function analysis, highlighting the significance of KRT15 in epidermal homeostasis and pathology.

The unique advantage of utilizing KRT15 Gene Knockout Cell Lines is their targeted approach, allowing researchers to avoid the off-target effects often associated with other gene editing methods. Moreover, the validated knockout lines come with robust characterization and documentation, ensuring reproducibility and confidence in experimental outcomes.

For researchers and clinicians, these cell lines provide an invaluable resource for advancing knowledge in keratinocyte biology, enabling innovative approaches to tackling skin-related diseases and improving therapeutic strategies.

With extensive expertise in developing cutting-edge biological products, our company is committed to providing high-quality KRT15 Gene Knockout Cell Lines and supporting researchers in their pursuit of scientific excellence.

Please note that all services are for research use only. Not intended for any clinical use.

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