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KLHL29 Knockout Cell Lines

Gene: KLHL29

Official Full Name: kelch like family member 29provided by HGNC

Gene Summary: Predicted to enable ubiquitin-like ligase-substrate adaptor activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be part of Cul3-RING ubiquitin ligase complex. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO30738 KLHL29 Knockout cell line (HeLa) Human KLHL29 1:3~1:6 Negative Online Inquiry
KO30739 KLHL29 Knockout cell line (HCT 116) Human KLHL29 1:2~1:4 Negative Online Inquiry
KO30740 KLHL29 Knockout cell line (HEK293) Human KLHL29 1:3~1:6 Negative Online Inquiry
KO30741 KLHL29 Knockout cell line (A549) Human KLHL29 1:3~1:4 Negative Online Inquiry

Background

KLHL29 Gene Knockout Cell Lines are specialized cellular models engineered to lack the KLHL29 gene, a member of the kelch-like protein family known for its role in various cellular processes, including protein folding, degradation, and stress responses. These knockout cell lines provide researchers with a powerful tool to investigate the precise functions and regulatory mechanisms associated with the KLHL29 protein, which is implicated in several biological pathways and disease mechanisms.

Through targeted gene editing techniques such as CRISPR-Cas9, these cell lines enable the study of the phenotypic consequences of KLHL29 loss. This can shed light on the gene's involvement in cellular homeostasis, pathways of cell signaling, and potential contributions to disease processes such as cancer or neurodegeneration. Researchers can utilize these models to study gene interactions, resilience to cellular stress, or the impact of KLHL29 on growth and differentiation, thus addressing critical questions in cellular and molecular biology.

The scientific importance of KLHL29 gene knockout cell lines is underscored by their applications in drug discovery and therapeutic development, as understanding the role of this gene may reveal novel targets for intervention. Moreover, the ability to generate knockout models tailored to specific research needs provides a significant advantage over traditional methodologies that rely on overexpression or knockdown strategies, which often do not yield clear mechanistic insights.

What sets our KLHL29 Gene Knockout Cell Lines apart from alternatives is the rigorous validation each line undergoes, ensuring a reliable and reproducible research outcome. Additionally, our commitment to providing customized solutions means that researchers can request specific modifications or experimental designs that cater to their unique study goals.

This product is invaluable for researchers and clinicians aiming to delve deeper into the functional biology of KLHL29, facilitating breakthroughs in understanding its role in health and disease. At our company, we pride ourselves on our extensive expertise in gene editing technologies and our dedication to providing high-quality biological products that empower scientific discovery.

Please note that all services are for research use only. Not intended for any clinical use.

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