Gene: KLF4
Official Full Name: KLF transcription factor 4provided by VGNC
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO01496 | KLF4 Knockout cell line(IPEC-J2) | Pig | KLF4 | 1:2~1:3 | Negative | Online Inquiry |
KO05635 | KLF4 Knockout cell line (HeLa) | Human | KLF4 | 1:3~1:6 | Negative | Online Inquiry |
KO05636 | KLF4 Knockout cell line (HCT 116) | Human | KLF4 | 1:2~1:4 | Negative | Online Inquiry |
KO05637 | KLF4 Knockout cell line (HEK293) | Human | KLF4 | 1:3~1:6 | Negative | Online Inquiry |
KO05638 | KLF4 Knockout cell line (A549) | Human | KLF4 | 1:3~1:4 | Negative | Online Inquiry |
KLF4 Gene Knockout Cell Lines are genetically engineered cell lines that have had the KLF4 gene (Kruppel-like factor 4) disrupted, enabling researchers to explore its functions and roles in various biological processes. KLF4 is a critical transcription factor involved in maintaining pluripotency and regulating cell differentiation, making these knockout cell lines invaluable for studying development, cancer biology, and stem cell research. The mechanism of action relies on the targeted disruption of the KLF4 gene using CRISPR/Cas9 technology, which enables precise edits to the genome, thereby allowing researchers to analyze the phenotypic consequences of losing KLF4 function.
The scientific importance of KLF4 Gene Knockout Cell Lines resides in their wide-ranging applications. In research, these cell lines provide insights into the molecular mechanisms of disease, particularly in cancer where aberrations in KLF4 expression are often observed. They are also crucial for elucidating the pathways governing cellular pluripotency and differentiation, facilitating advances in regenerative medicine. Moreover, these knockout lines serve as models for drug development, enabling the identification of therapeutic targets and screening for possible compounds.
What sets KLF4 Gene Knockout Cell Lines apart from other genetic models is the precision and reliability of gene editing achieved through established technologies. Compared to traditional methods, these cell lines offer a faster and more efficient approach to understanding gene function without the cumbersome limitations of older knockout techniques. Additionally, they provide reproducible results across various experiments, enhancing the reliability of research findings.
For researchers and clinicians alike, the value of KLF4 Gene Knockout Cell Lines is immeasurable. They present opportunities to deepen understanding of complex biological systems and pave the way for innovative therapeutic strategies. By utilizing these tools, scientists can accelerate breakthroughs in developmental biology and cancer treatment.
At our company, we pride ourselves on our robust expertise in genetic engineering and biological product development. Our commitment to quality and innovation ensures that researchers have access to cutting-edge tools, such as KLF4 Gene Knockout Cell Lines, that enhance their research capabilities and outcomes.
Please note that all services are for research use only. Not intended for any clinical use.
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