Gene: KLC3
Official Full Name: kinesin light chain 3provided by HGNC
Gene Summary: This gene encodes a member of the kinesin light chain gene family. Kinesins are molecular motors involved in the transport of cargo along microtubules, and are composed of two kinesin heavy chain (KHC) and two kinesin light chain (KLC) molecules. KLCs are thought to typically be involved in binding cargo and regulating kinesin activity. In the rat, a protein similar to this gene product is expressed in post-meiotic spermatids, where it associates with structural components of sperm tails and mitochondria. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO23661 | KLC3 Knockout cell line (HeLa) | Human | KLC3 | 1:3~1:6 | Negative | Online Inquiry |
KO23662 | KLC3 Knockout cell line (HCT 116) | Human | KLC3 | 1:2~1:4 | Negative | Online Inquiry |
KO23663 | KLC3 Knockout cell line (HEK293) | Human | KLC3 | 1:3~1:6 | Negative | Online Inquiry |
KO23664 | KLC3 Knockout cell line (A549) | Human | KLC3 | 1:3~1:4 | Negative | Online Inquiry |
KLC3 Gene Knockout Cell Lines are genetically engineered cellular models designed to facilitate the study of the KLC3 gene's role in cellular processes. KLC3, or kinesin light chain 3, is part of the kinesin protein family, which is crucial for intracellular transport mechanisms. By creating knockout versions of these cell lines, researchers can observe phenotypic changes and gain insights into the gene's specific functions in microtubule-based transport and cellular signaling pathways.
The KLC3 gene knockout involves the targeted deletion of the gene, allowing scientists to dissect its contributions to various biological processes, including neuronal development, cell division, and receptor trafficking. The elimination of KLC3 can be analyzed to assess the efficacy of alternative transport mechanisms, offering a clear perspective on the reliance of cellular systems on this particular kinesin. This cellular tool not only aids in delineating the physiological implications of KLC3 but also enhances our understanding of broader cellular transport dynamics.
The scientific importance of KLC3 Gene Knockout Cell Lines extends to numerous applications in fundamental research and clinical contexts. They serve as essential models for studying motor protein dysfunctions associated with neurodegenerative diseases, cancer, and metabolic disorders. These cell lines also hold potential for drug discovery, where screening compounds against these modified cells can uncover therapeutic targets.
Compared to traditional research methodologies, the KLC3 Gene Knockout Cell Lines provide a precise and streamlined approach to gene function studies, minimizing background variations associated with non-specific targeting. Their ability to facilitate controlled experiments makes them a superior option for researchers looking to accelerate discoveries in cell biology.
Investing in KLC3 Gene Knockout Cell Lines empowers researchers and clinicians alike, offering a reliable platform for innovative research that can lead to groundbreaking discoveries in health and disease. As a company renowned for our commitment to cutting-edge biotechnology, we pride ourselves on providing high-quality genetic resources that ignite scientific inquiry and support continuous advancement in life sciences.
Please note that all services are for research use only. Not intended for any clinical use.
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