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KIF2C Knockout Cell Lines

Gene: KIF2C

Official Full Name: kinesin family member 2Cprovided by HGNC

Gene Summary: This gene encodes a kinesin-like protein that functions as a microtubule-dependent molecular motor. The encoded protein can depolymerize microtubules at the plus end, thereby promoting mitotic chromosome segregation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO31319 KIF2C Knockout cell line (HeLa) Human KIF2C 1:3~1:6 Negative Online Inquiry
KO31320 KIF2C Knockout cell line (HCT 116) Human KIF2C 1:2~1:4 Negative Online Inquiry
KO31321 KIF2C Knockout cell line (HEK293) Human KIF2C 1:3~1:6 Negative Online Inquiry
KO31322 KIF2C Knockout cell line (A549) Human KIF2C 1:3~1:4 Negative Online Inquiry

Background

KIF2C Gene Knockout Cell Lines are specialized cellular models in which the KIF2C gene, a crucial player in mitotic spindle dynamics and chromosome segregation, has been intentionally disrupted. This knockout facilitates the investigation of KIF2C’s role in cellular processes such as mitosis, apoptosis, and cancer progression, enabling researchers to elucidate the underlying mechanisms of chromosome instability associated with various diseases, particularly in oncology.

The primary function of KIF2C is to regulate the depolymerization of microtubules during mitosis, thereby ensuring accurate chromosome alignment and segregation. By using KIF2C Gene Knockout Cell Lines, scientists can directly observe the consequences of KIF2C loss on cell cycle progression and ensure that conditions critical for tumor development are studied under controlled environments. These cell lines aid in the assessment of KIF2C’s interactions with other cellular pathways and its downstream effects on cell proliferation and survival.

The significance of KIF2C knockout models is underscored in research and clinical applications, particularly in the development of targeted cancer therapies. Understanding the molecular breakdown in the absence of KIF2C can provide pivotal insights into potential interventions that aim to restore genomic stability in cancerous cells. Additionally, these models facilitate high-throughput screening of drug candidates, ultimately accelerating the discovery of novel therapeutics with implications in cancer treatment.

Compared to traditional models, KIF2C Gene Knockout Cell Lines offer enhanced specificity and reproducibility for studying gene function, allowing researchers to circumvent confounding factors that may arise in non-knockout systems. Our product is designed with stringent quality control measures to ensure the reliability of experimental results, providing a distinct advantage over alternative models.

The value of KIF2C Gene Knockout Cell Lines extends beyond research applications; they are essential tools for clinicians and biotechnologists aiming to bridge the gap between basic science and therapeutic development. By choosing our product, users gain access to innovative technology backed by our company's expertise in creating high-quality biological products tailored for cutting-edge research in life sciences.

Please note that all services are for research use only. Not intended for any clinical use.

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