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KIF15 Knockout Cell Lines

Gene: KIF15

Official Full Name: kinesin family member 15provided by HGNC

Gene Summary: Predicted to enable ATP hydrolysis activity; microtubule binding activity; and plus-end-directed microtubule motor activity. Predicted to be involved in centrosome separation; microtubule-based movement; and mitotic spindle assembly. Located in membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO16731 KIF15 Knockout cell line (HeLa) Human KIF15 1:3~1:6 Negative Online Inquiry
KO16732 KIF15 Knockout cell line (HCT 116) Human KIF15 1:2~1:4 Negative Online Inquiry
KO16733 KIF15 Knockout cell line (HEK293) Human KIF15 1:3~1:6 Negative Online Inquiry
KO16734 KIF15 Knockout cell line (A549) Human KIF15 1:3~1:4 Negative Online Inquiry

Background

KIF15 Gene Knockout Cell Lines are a cutting-edge tool designed for cellular and molecular biology research, specifically targeting the KIF15 gene, which encodes a motor protein involved in mitosis. These genetically modified cell lines are created through precise gene editing techniques, enabling the complete disruption of KIF15 expression. This knockout capability permits extensive investigation into the gene's role in cellular processes, such as chromosome segregation and spindle dynamics during cell division.

The primary function of the KIF15 gene product is its involvement in the transport of cellular cargo along microtubules, crucial for proper cell division. By utilizing KIF15 Gene Knockout Cell Lines, researchers can explore the downstream effects of KIF15 loss on cellular mechanisms, including potential impacts on cancerous cell proliferation, response to therapeutic agents, and overall cell cycle regulation. This makes the product invaluable for both basic biological research and translational studies.

Scientifically, the KIF15 Gene Knockout Cell Lines hold significant importance in unraveling the complexities of mitotic pathways and their implications in oncogenesis. In clinical settings, understanding the function of KIF15 could lead to novel therapeutic targets for cancer treatment, particularly in tumors characterized by dysregulated cell division.

Compared to standard cell lines or non-specific gene silencing methods, KIF15 Gene Knockout Cell Lines provide a distinct advantage by delivering a complete and permanent loss of gene function, enabling more accurate modeling of KIF15-null phenotypes. This specificity mitigates off-target effects often seen with conventional RNA interference techniques, ensuring clarity in experimental outcomes.

For researchers and clinicians focused on cell biology, cancer research, or therapeutic development, KIF15 Gene Knockout Cell Lines are an invaluable asset that streamlines experimental design and enhances data reliability. Our company is committed to providing high-quality biological products backed by extensive expertise in genetic engineering and cellular analysis, ensuring researchers have access to state-of-the-art tools that drive scientific discovery forward.

Please note that all services are for research use only. Not intended for any clinical use.

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