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KHK Knockout Cell Lines

Gene: KHK

Official Full Name: ketohexokinaseprovided by HGNC

Gene Summary: This gene encodes ketohexokinase that catalyzes conversion of fructose to fructose-1-phosphate. The product of this gene is the first enzyme with a specialized pathway that catabolizes dietary fructose. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO36949 KHK Knockout cell line (HeLa) Human KHK 1:3~1:6 Negative Online Inquiry
KO36950 KHK Knockout cell line (HCT 116) Human KHK 1:2~1:4 Negative Online Inquiry
KO36951 KHK Knockout cell line (HEK293) Human KHK 1:3~1:6 Negative Online Inquiry
KO36952 KHK Knockout cell line (A549) Human KHK 1:3~1:4 Negative Online Inquiry

Background

KHK Gene Knockout Cell Lines are specifically engineered cellular models that allow researchers to systematically investigate the functions of specific genes by disabling them through targeted inactivation. These cell lines utilize advanced CRISPR/Cas9 gene-editing technology, which modifies the genome to create precise deletions or mutations. This modification permits researchers to study gene function, elucidate biological pathways, and assess the impact of gene loss on cellular behavior.

The key function of KHK Gene Knockout Cell Lines lies in their ability to facilitate targeted gene silencing, enabling a clearer understanding of gene function in both normal and disease states. Upon gene knockout, researchers can observe phenotypic changes, investigate compensatory mechanisms, and validate drug targets. The high specificity and efficiency of the CRISPR/Cas9 system employed ensures reproducibility and reliability in experimental outcomes, making these cell lines particularly helpful in both basic and applied research.

In the scientific community, the importance of KHK Gene Knockout Cell Lines is substantial. They serve critical roles in genetic research, disease modeling, and drug discovery. By enabling the study of gene function in a controlled environment, these cell lines aid in the development of therapeutic interventions and contribute to our understanding of diseases, including cancer, genetic disorders, and infectious diseases.

What sets KHK Gene Knockout Cell Lines apart from conventional knockout models or RNA interference approaches is their precision, speed, and ease of use. The ability to create multiple gene knockouts within a single cell line, as well as the capacity for high-throughput screening applications, positions KHK cell lines as an advanced tool for contemporary research needs.

For researchers and clinicians, the significance of utilizing KHK Gene Knockout Cell Lines lies in their potential to unveil novel insights into gene function and their implications in health and disease. Their reliability and flexibility can streamline research timelines, enhance experimental outcomes, and drive impactful scientific discoveries.

At KHK, we pride ourselves on our extensive expertise in gene editing technologies and our commitment to delivering high-quality biological products. Our Gene Knockout Cell Lines are rigorously validated and designed to meet the evolving demands of the scientific community, ensuring that our clients have the resources necessary for success in their research endeavors.

Please note that all services are for research use only. Not intended for any clinical use.

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