Gene: KCTD3
Official Full Name: potassium channel tetramerization domain containing 3provided by HGNC
Gene Summary: This gene encodes a member of the potassium channel tetramerization-domain containing (KCTD) protein family. Members of this protein family regulate the biophysical characteristics of ion channels. In mouse, this protein interacts with hyperpolarization-activated cyclic nucleotide-gated channel complex 3 and enhances its cell surface expression and current density. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO22971 | KCTD3 Knockout cell line (HeLa) | Human | KCTD3 | 1:3~1:6 | Negative | Online Inquiry |
KO22972 | KCTD3 Knockout cell line (HCT 116) | Human | KCTD3 | 1:2~1:4 | Negative | Online Inquiry |
KO22973 | KCTD3 Knockout cell line (HEK293) | Human | KCTD3 | 1:3~1:6 | Negative | Online Inquiry |
KO22974 | KCTD3 Knockout cell line (A549) | Human | KCTD3 | 1:3~1:4 | Negative | Online Inquiry |
KCTD3 Gene Knockout Cell Lines are genetically engineered model systems that allow researchers to study the function of the KCTD3 gene by rendering it non-functional through targeted gene knockout techniques. These cell lines provide a crucial tool for investigating the biological roles of KCTD3, which is implicated in various cellular processes such as signal transduction, regulation of intracellular signaling pathways, and cellular proliferation. By disrupting the normal expression of the KCTD3 gene, these knockout cell lines facilitate the exploration of phenotypic changes associated with its loss, thereby allowing researchers to elucidate the gene's role in health and disease.
The mechanisms underlying the functionality of KCTD3 Gene Knockout Cell Lines involve the CRISPR/Cas9 gene-editing technology, which precisely alters the genomic DNA to create a complete KO of the target gene. This precision not only ensures the efficacy of the knockout but also minimizes off-target effects that could confound experimental outcomes.
Scientifically, the importance of these cell lines is underscored by their broad applicability in both basic research and therapeutic development. They are instrumental in studies related to neurodegenerative disorders, cancer biology, and gene therapy, among others. Researchers can leverage these knockout lines to perform functional assays, evaluate the impact of KCTD3 on cellular behavior, and screen for potential therapeutic interventions.
Compared to other models such as transient transfection systems or complete animal models, KCTD3 Gene Knockout Cell Lines offer several advantages. They provide a stable environment for consistent replication of experiments, create a controlled setting for high-throughput screening, and facilitate quicker results due to the elimination of variables associated with in vivo studies.
For researchers and clinicians focused on molecular mechanisms and pathways involving KCTD3, these knockout cell lines are invaluable. They empower scientific inquiry, enabling investigations that may lead to innovative therapeutic strategies and a deeper understanding of complex biological systems.
Our company has extensive expertise in the development of advanced genetic models tailored for various research applications, ensuring that we deliver high-quality products designed to support cutting-edge scientific discovery.
Please note that all services are for research use only. Not intended for any clinical use.
If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.
There is no product in your cart. |
CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.