Gene: KCTD10
Official Full Name: potassium channel tetramerization domain containing 10provided by HGNC
Gene Summary: The protein encoded by this gene binds proliferating cell nuclear antigen (PCNA) and may be involved in DNA synthesis and cell proliferation. In addition, the encoded protein may be a tumor suppressor. Several protein-coding and non-protein coding transcript variants have been found for this gene. [provided by RefSeq, Dec 2015]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO25321 | KCTD10 Knockout cell line (HeLa) | Human | KCTD10 | 1:3~1:6 | Negative | Online Inquiry |
KO25322 | KCTD10 Knockout cell line (HCT 116) | Human | KCTD10 | 1:2~1:4 | Negative | Online Inquiry |
KO25323 | KCTD10 Knockout cell line (HEK293) | Human | KCTD10 | 1:3~1:6 | Negative | Online Inquiry |
KO25324 | KCTD10 Knockout cell line (A549) | Human | KCTD10 | 1:3~1:4 | Negative | Online Inquiry |
KCTD10 Gene Knockout Cell Lines are genetically engineered cell lines characterized by the disruption of the KCTD10 gene, which plays a crucial role in various cellular processes, including neuronal signaling and cellular stress responses. These cell lines are created utilizing advanced CRISPR-Cas9 technology, enabling precise gene editing that allows researchers to study the functional consequences of KCTD10 gene loss in a controlled environment. By generating KCTD10 knockout models, scientists can examine alterations in signaling pathways, receptor interactions, and cell viability, paving the way for insights into diseases where KCTD10 is implicated.
The primary mechanism of action involves the introduction of a double-strand break in the KCTD10 gene, prompting cellular repair processes that result in a non-functional gene variant. This genetic modification facilitates in-depth exploration of KCTD10's role in cellular processes, neurodevelopment, and potential links to diseases such as schizophrenia or neurological disorders.
In a research context, KCTD10 Gene Knockout Cell Lines are invaluable tools for elucidating the genetic and molecular underpinnings of complex biological phenomena. Their application extends to pharmacological studies, allowing for the identification of drug targets and the assessment of therapeutic efficacy in the absence of KCTD10.
Compared to traditional methods of gene silencing, such as siRNA or shRNA, KCTD10 knockout cell lines offer a more permanent and stable solution, effectively eliminating variability associated with transient knockdown approaches. This stability serves as a significant advantage for long-term studies, enabling reproducibility and reliability in experimental outcomes.
For researchers and clinicians keen on unraveling the functional role of KCTD10 in health and disease, these knockout cell lines provide a robust platform for innovative studies. The ability to directly manipulate genes and study their effects in a cellular context enhances the overall understanding of genetic contributions to various pathologies, making KCTD10 Gene Knockout Cell Lines a valuable asset.
With a commitment to advancing genetic research and providing cutting-edge biological products, our company specializes in high-quality gene knockout models designed to support the needs of the scientific community. We pride ourselves on our expertise in genetic engineering, ensuring that our products meet the highest standards of precision and utility in research applications.
Please note that all services are for research use only. Not intended for any clinical use.
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