Gene: KBTBD6
Official Full Name: kelch repeat and BTB domain containing 6provided by HGNC
Gene Summary: Predicted to enable ubiquitin-like ligase-substrate adaptor activity. Involved in proteasome-mediated ubiquitin-dependent protein catabolic process; protein K48-linked ubiquitination; and regulation of Rac protein signal transduction. Located in cytoplasm and nucleus. Part of Cul3-RING ubiquitin ligase complex. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO23902 | KBTBD6 Knockout cell line (HeLa) | Human | KBTBD6 | 1:3~1:6 | Negative | Online Inquiry |
KO23903 | KBTBD6 Knockout cell line (HCT 116) | Human | KBTBD6 | 1:2~1:4 | Negative | Online Inquiry |
KO23904 | KBTBD6 Knockout cell line (HEK293) | Human | KBTBD6 | 1:3~1:6 | Negative | Online Inquiry |
KO23905 | KBTBD6 Knockout cell line (A549) | Human | KBTBD6 | 1:3~1:4 | Negative | Online Inquiry |
KBTBD6 Gene Knockout Cell Lines are highly specialized cellular models derived from genetically modified organisms that have had the KBTBD6 gene selectively inactivated. This innovative product allows researchers to study the function of KBTBD6 with high precision, focusing on its role in cellular processes such as protein degradation, cellular signaling, and response mechanisms to stressors. The knockout strategy involves sophisticated gene editing technologies, such as CRISPR-Cas9, ensuring that the resultant cell lines provide a clean background for eliminating confounding variables.
The key mechanism underlying the utility of these cell lines lies in their ability to facilitate detailed investigations into the biological significance of the KBTBD6 gene. By inducing a knockout, researchers can elucidate the gene's influence on various phenotypic expressions, cell cycle regulation, and apoptosis. This information is invaluable for understanding pathologies where KBTBD6 is implicated, including certain cancers and neurological disorders.
From a scientific perspective, KBTBD6 Gene Knockout Cell Lines represent an important advancement in biomedical research. Their applications span drug discovery, functional genomics, and the study of gene interactions within pathways related to neurodegenerative diseases and beyond. The ability to observe the absence of KBTBD6 allows for the articulation of its role in disease mechanisms, thereby potentially guiding future therapeutic strategies.
Compared to traditional methods involving chemical inhibition or RNA interference, these knockout cell lines offer significant advantages. They provide a more stable and long-term model for studying gene function without the variability associated with transient transfections or chemical agents. This results in reproducible and robust data, which enhances the translational potential of the research findings.
Researchers and clinicians looking to gain clarity on the pathways affected by KBTBD6 can derive immense value from these specialized cell lines. With their precision and reliability, they represent a critical resource for advancing knowledge in molecular biology and therapeutic development.
Our company specializes in producing high-quality, fully characterized cell lines that meet the rigorous demands of modern research. With a commitment to innovation and excellence, we ensure that our products, like the KBTBD6 Gene Knockout Cell Lines, empower scientific exploration and discovery across diverse fields.
Please note that all services are for research use only. Not intended for any clinical use.
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