Gene: KBTBD2
Official Full Name: kelch repeat and BTB domain containing 2provided by HGNC
Gene Summary: Enables ubiquitin-like ligase-substrate adaptor activity. Involved in protein K48-linked ubiquitination and regulation of cellular response to insulin stimulus. Is active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO28577 | KBTBD2 Knockout cell line (HeLa) | Human | KBTBD2 | 1:3~1:6 | Negative | Online Inquiry |
KO28578 | KBTBD2 Knockout cell line (HCT 116) | Human | KBTBD2 | 1:2~1:4 | Negative | Online Inquiry |
KO28579 | KBTBD2 Knockout cell line (HEK293) | Human | KBTBD2 | 1:3~1:6 | Negative | Online Inquiry |
KO28580 | KBTBD2 Knockout cell line (A549) | Human | KBTBD2 | 1:3~1:4 | Negative | Online Inquiry |
KBTBD2 Gene Knockout Cell Lines are specialized cellular models engineered to lack the KBTBD2 gene, a component involved in key cellular processes such as protein homeostasis and cellular signaling pathways. These knockout cell lines serve as crucial tools for researchers exploring the molecular mechanisms and functional roles of KBTBD2 in various biological contexts, including cancer biology, neurobiology, and cellular stress responses.
The primary function of KBTBD2 is associated with the regulation of protein stability and turnover through its interaction with ubiquitin-proteasome pathways. By knocking out this gene, researchers can observe the resulting phenotypic and molecular changes, providing insights into its role in cellular growth, differentiation, and response to external stimuli. This mechanistic understanding is vital for elucidating the gene’s impact on pathophysiological conditions and can inform targeted therapeutic strategies.
In scientific research and clinical settings, KBTBD2 Gene Knockout Cell Lines offer significant advantages. They allow for the precise study of gene function without the confounding effects of compensatory pathways that often complicate the interpretation of results in wild-type models. Compared to traditional knockdown models using shRNA or siRNA, gene knockout offers a more permanent solution for examining gene function, thereby enhancing experimental reproducibility and robustness.
For researchers and clinicians focused on genetic and molecular pathways, the KBTBD2 Gene Knockout Cell Lines stand as an invaluable resource. They facilitate advanced studies in gene regulation, support drug discovery initiatives, and help develop innovative therapeutics based on the profound insights gained from gene function assays.
Our company specializes in producing high-quality genetic models designed for cutting-edge research. With a commitment to scientific excellence and customer support, we ensure that our products empower researchers to advance their understanding of complex biological systems through reliable and innovative tools.
Please note that all services are for research use only. Not intended for any clinical use.
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