Gene: JADE2
Official Full Name: jade family PHD finger 2provided by HGNC
Gene Summary: Enables histone H4K12 acetyltransferase activity; histone H4K5 acetyltransferase activity; and histone H4K8 acetyltransferase activity. Contributes to histone H3K14 acetyltransferase activity. Involved in regulation of DNA biosynthetic process; regulation of DNA replication; and regulation of cell cycle. Located in nucleoplasm. Part of histone acetyltransferase complex. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO29424 | JADE2 Knockout cell line (HeLa) | Human | JADE2 | 1:3~1:6 | Negative | Online Inquiry |
KO29425 | JADE2 Knockout cell line (HCT 116) | Human | JADE2 | 1:2~1:4 | Negative | Online Inquiry |
KO29426 | JADE2 Knockout cell line (HEK293) | Human | JADE2 | 1:3~1:6 | Negative | Online Inquiry |
KO29427 | JADE2 Knockout cell line (A549) | Human | JADE2 | 1:3~1:4 | Negative | Online Inquiry |
JADE2 Gene Knockout Cell Lines are genetically modified cellular models specifically designed to facilitate the study of the JADE2 gene's function in various biological contexts. These cell lines provide a powerful tool for researchers aiming to investigate the molecular mechanisms underlying cellular processes, including gene regulation, DNA repair, and chromatin remodeling.
The core function of JADE2 Gene Knockout Cell Lines involves the targeted disruption of the JADE2 gene, which encodes a protein implicated in the regulation of histone modifications and the maintenance of genomic integrity. By utilizing CRISPR-Cas9 technology, these knockout cell lines offer precise gene editing capabilities that enable researchers to observe phenotypic alterations and elucidate the biological roles of JADE2. This mechanism allows for the assessment of cellular responses to environmental stimuli, drug treatments, or disease models, thereby providing critical insights into cancer biology, developmental processes, and other pathophysiological states.
The scientific importance of JADE2 Gene Knockout Cell Lines extends into both basic research and clinical applications. In research settings, these models assist in unveiling the functional consequences of the loss of JADE2, which can be pivotal in identifying potential therapeutic targets for conditions such as cancer or genetic disorders. In clinical applications, understanding JADE2's role can lead to the development of novel treatment strategies that target pathways affected by its dysregulation.
What sets our JADE2 Gene Knockout Cell Lines apart from alternative products is the rigor of our validation process, which ensures high specificity and reliability of gene knockout. Additionally, these cell lines are available in various formats and types, allowing for tailored applications across different experimental designs. The ease of use and adaptability of our knockout models deliver significant time and cost savings by streamlining experimental workflows.
Researchers and clinicians will find our JADE2 Gene Knockout Cell Lines invaluable due to their ability to drive innovative research and accelerate discovery. They enable users to greatly enhance their understanding of complex biological systems and make informed decisions in drug development and disease research.
With years of expertise in genetic engineering and a commitment to quality, our company stands at the forefront of biological product innovation. We are dedicated to providing researchers with cutting-edge tools that enhance scientific discovery and clinical translation, ensuring impactful advancements in biological research.
Please note that all services are for research use only. Not intended for any clinical use.
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