Gene: ITFG2
Official Full Name: integrin alpha FG-GAP repeat containing 2provided by HGNC
Gene Summary: Involved in cellular response to amino acid starvation; cellular response to glucose starvation; and negative regulation of TORC1 signaling. Located in Golgi apparatus and lysosomal membrane. Part of KICSTOR complex. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO16874 | ITFG2 Knockout cell line (HeLa) | Human | ITFG2 | 1:3~1:6 | Negative | Online Inquiry |
KO16875 | ITFG2 Knockout cell line (HCT 116) | Human | ITFG2 | 1:2~1:4 | Negative | Online Inquiry |
KO16876 | ITFG2 Knockout cell line (HEK293) | Human | ITFG2 | 1:3~1:6 | Negative | Online Inquiry |
KO16877 | ITFG2 Knockout cell line (A549) | Human | ITFG2 | 1:3~1:4 | Negative | Online Inquiry |
ITFG2 Gene Knockout Cell Lines are genetically engineered cell lines in which the ITFG2 gene has been specifically disrupted or "knocked out". The ITFG2 gene is vital for various cellular processes, including cell adhesion, migration, and signaling pathways that are crucial for maintaining cellular integrity and responding to extracellular stimuli. By utilizing targeted gene editing technologies such as CRISPR-Cas9, these knockout cell lines provide researchers with a powerful tool to investigate the precise role of ITFG2 in various biological contexts.
The primary function of ITFG2 Gene Knockout Cell Lines lies in their ability to enable detailed studies of gene function and cellular behavior in a controlled environment. Researchers can observe phenotypic changes that occur when the ITFG2 pathway is inhibited, thus clarifying the gene's involvement in processes such as tumorigenesis, immune response, and tissue development. The knockout cell lines can also serve as an excellent platform for drug discovery, given their utility in assessing the impact of therapeutic compounds targeting this pathway.
In scientific research and clinical applications, ITFG2 Gene Knockout Cell Lines hold significant importance. They are invaluable for investigating diseases, particularly in understanding cancer biology where the dysregulation of adhesion and signaling pathways can result in malignancies. These cell lines can also be instrumental in the development of gene therapies or in assessing the efficacy of novel drugs designed to target related pathways.
Compared to conventional methods of gene editing, ITFG2 Gene Knockout Cell Lines come with distinct advantages. They offer high specificity and efficiency in gene disruption, thereby minimizing off-target effects typical of older gene-editing techniques. Furthermore, these cell lines are usually well-characterized and can be easily incorporated into existing experimental workflows, saving researchers time and resources.
The inherent value of ITFG2 Gene Knockout Cell Lines transcends mere utility; they represent a forward leap in understanding complex biological systems. Researchers and clinicians can leverage these advanced tools to unlock new insights into gene function and disease mechanisms, ultimately leading to innovative therapeutic strategies. Our company is committed to providing high-quality biological products, and with our expertise in cell line development and gene editing, we continue to support the advancement of scientific discovery and application in a rapidly evolving research landscape.
Please note that all services are for research use only. Not intended for any clinical use.
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