Gene: IQGAP3
Official Full Name: IQ motif containing GTPase activating protein 3provided by HGNC
Gene Summary: Enables calmodulin binding activity and myosin VI light chain binding activity. Predicted to be involved in mitotic actomyosin contractile ring assembly actin filament organization. Predicted to act upstream of or within several processes, including G1/S transition of mitotic cell cycle; intracellular signaling cassette; and regulation of macromolecule metabolic process. Predicted to be located in cytosol. Predicted to be active in cell cortex. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO26785 | IQGAP3 Knockout cell line (HeLa) | Human | IQGAP3 | 1:3~1:6 | Negative | Online Inquiry |
KO26786 | IQGAP3 Knockout cell line (HCT 116) | Human | IQGAP3 | 1:2~1:4 | Negative | Online Inquiry |
KO26787 | IQGAP3 Knockout cell line (HEK293) | Human | IQGAP3 | 1:3~1:6 | Negative | Online Inquiry |
KO26788 | IQGAP3 Knockout cell line (A549) | Human | IQGAP3 | 1:3~1:4 | Negative | Online Inquiry |
IQGAP3 Gene Knockout Cell Lines are specialized cellular models engineered for the study of the IQ Motif Containing GTPase Activating Protein 3 (IQGAP3), a scaffold protein implicated in various cellular processes including cytoskeletal organization, signal transduction, and cellular adhesion. These knockout cell lines are created using advanced CRISPR-Cas9 gene editing technology to disrupt the IQGAP3 gene, allowing researchers to investigate the gene's functional role in both physiological and pathological contexts.
The primary function of the IQGAP3 knockout cell lines is to facilitate the elucidation of the molecular mechanisms underlying IQGAP3's involvement in cellular signaling pathways. By studying these cells, researchers can explore the consequences of IQGAP3 absence on cell migration, proliferation, and apoptosis, providing valuable insights into its role in cancer biology, neurodevelopmental disorders, and other diseases.
In scientific and clinical settings, these cell lines are essential tools for discovering novel therapeutic targets and developing drugs aimed at conditions where IQGAP3 plays a critical role. Their utility in high-throughput screening and in vivo functional assays can help accelerate the pace of research while enhancing the understanding of complex biological systems.
Unlike traditional cell lines, which may express varying levels of the target gene, the IQGAP3 Gene Knockout Cell Lines offer a consistent genetic background devoid of IQGAP3 expression, resulting in more reproducible outcomes. This precision in gene targeting sets them apart from alternatives and enables researchers to conduct more reliable experiments, ultimately refining their hypotheses and experimental designs.
Investing in IQGAP3 Gene Knockout Cell Lines translates to access to a high-quality, versatile research tool that can significantly impact the advancement of biomedical research. Our company, renowned for its commitment to precision genetic tools, leverages cutting-edge technology to deliver reliable and innovative solutions tailored to meet the diverse needs of researchers in academia and industry. Through continuous support and expertise, we aim to empower scientists in their quest for groundbreaking discoveries.
Please note that all services are for research use only. Not intended for any clinical use.
If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.
There is no product in your cart. |
CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.