Gene: IPMK
Official Full Name: inositol polyphosphate multikinaseprovided by HGNC
Gene Summary: This gene encodes a member of the inositol phosphokinase family. The encoded protein has 3-kinase, 5-kinase and 6-kinase activities on phosphorylated inositol substrates. The encoded protein plays an important role in the biosynthesis of inositol 1,3,4,5,6-pentakisphosphate, and has a preferred 5-kinase activity. This gene may play a role in nuclear mRNA export. Pseudogenes of this gene are located on the long arm of chromosome 13 and the short arm of chromosome 19. [provided by RefSeq, Dec 2010]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO07828 | IPMK Knockout cell line (HeLa) | Human | IPMK | 1:3~1:6 | Negative | Online Inquiry |
KO07829 | IPMK Knockout cell line (HCT 116) | Human | IPMK | 1:2~1:4 | Negative | Online Inquiry |
KO07830 | IPMK Knockout cell line (HEK293) | Human | IPMK | 1:3~1:6 | Negative | Online Inquiry |
KO07831 | IPMK Knockout cell line (A549) | Human | IPMK | 1:3~1:4 | Negative | Online Inquiry |
IPMK Gene Knockout Cell Lines are specialized cellular models that have been engineered to have a disrupted IPMK (Inositol Polyphosphate Multikinase) gene. This gene plays a critical role in various cellular processes, including inositol signaling pathways, which are essential for cell growth, differentiation, and apoptosis. By employing CRISPR/Cas9 technology, researchers can create precise knockout cell lines that lack functional IPMK, allowing for detailed studies of its role in biological systems.
The key function of these knockout cell lines lies in their ability to elucidate the molecular mechanisms through which IPMK influences cellular physiology. With the loss of IPMK functionality, researchers can observe changes in cell behavior, metabolic pathways, and responses to external stimuli, providing insights into its contributions to cancer biology, metabolism, and neurodegeneration. This makes IPMK Gene Knockout Cell Lines a powerful tool for studying disease mechanisms and potential therapeutic targets.
Scientifically, the availability of these cell lines enhances research capabilities in both academic and clinical settings. They allow scientists to investigate the functional implications of IPMK modulation, explore gene interactions, and screen potential drug candidates that may restore normal cellular functions. The knockout model provides a clean genetic background, thus eliminating confounding variables that may arise from other biological factors, giving researchers confidence in their findings.
Compared to alternative methods such as pharmacological inhibition or RNA interference, IPMK Gene Knockout Cell Lines offer a stable and reproducible system that allows for long-term studies and high-throughput screening. This specificity and reliability make them an invaluable resource in the functional genomics toolbox.
For researchers, clinicians, and biopharmaceutical companies, the utility of IPMK Gene Knockout Cell Lines is profound. They represent a cutting-edge approach to understanding the intricate roles of genes in health and disease, facilitating the development of targeted therapies and advanced biotechnological applications.
Our company specializes in generating high-quality, precisely engineered biological research tools, ensuring that scientists have access to the most effective models to advance their research endeavors efficiently and effectively.
Please note that all services are for research use only. Not intended for any clinical use.
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