Gene: INPP1
Official Full Name: inositol polyphosphate-1-phosphataseprovided by HGNC
Gene Summary: This gene encodes the enzyme inositol polyphosphate-1-phosphatase, one of the enzymes involved in phosphatidylinositol signaling pathways. This enzyme removes the phosphate group at position 1 of the inositol ring from the polyphosphates inositol 1,4-bisphosphate and inositol 1,3,4-trisphophosphate. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO07800 | INPP1 Knockout cell line (HeLa) | Human | INPP1 | 1:3~1:6 | Negative | Online Inquiry |
KO07801 | INPP1 Knockout cell line (HCT 116) | Human | INPP1 | 1:2~1:4 | Negative | Online Inquiry |
KO07802 | INPP1 Knockout cell line (HEK293) | Human | INPP1 | 1:3~1:6 | Negative | Online Inquiry |
KO07803 | INPP1 Knockout cell line (A549) | Human | INPP1 | 1:3~1:4 | Negative | Online Inquiry |
INPP1 Gene Knockout Cell Lines are a specialized biological model system designed to investigate the functional roles of the INPP1 gene, which encodes for inositol polyphosphate 1-phosphatase. These cell lines enable researchers to study the gene's impact on cellular processes such as phosphoinositide metabolism, signaling pathways, and overall cellular homeostasis. Utilizing CRISPR/Cas9 gene editing technology, the INPP1 gene is precisely disrupted, resulting in a knockout model that allows for in-depth analysis of the gene's biological functions.
The primary function of these cell lines is to model the loss of INPP1 activity, enabling the examination of cellular mechanisms affected by decreased inositol phosphate signaling. Researchers can investigate the implications of this knockout on various pathways associated with metabolic regulation, apoptosis, and cell proliferation. This approach provides valuable insights into the potential roles of INPP1 in conditions such as cancer, neurodegeneration, and metabolic disorders.
The scientific importance of INPP1 Gene Knockout Cell Lines in research settings cannot be overstated. These models facilitate high-throughput screening for potential therapeutic targets and help elucidate the molecular mechanisms underlying disease states. In clinical research, understanding the role of INPP1 can lead to novel intervention strategies that modify disease progression and improve patient outcomes.
Compared to alternative models, such as overexpression systems or wild-type lines, the specific advantages of the INPP1 knockout cell lines include their ability to minimize confounding factors that may arise from residual gene function. This specificity can yield clearer insights and improve the reliability of experimental results.
For researchers, clinicians, and biopharmaceutical developers, these cell lines represent a powerful tool that enables deeper understanding of complex biological systems. Their application can drive forward innovative research and accelerate the development of targeted therapies.
As a leader in the field of genetic model systems, our company is dedicated to providing high-quality biological tools, including the INPP1 Gene Knockout Cell Lines, to foster groundbreaking research and improve clinical applications across various fields.
Please note that all services are for research use only. Not intended for any clinical use.
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