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IGSF3 Knockout Cell Lines

Gene: IGSF3

Official Full Name: immunoglobulin superfamily member 3provided by HGNC

Gene Summary: The protein encoded by this gene is an immunoglobulin-like membrane protein containing several V-type Ig-like domains. A mutation in this gene has been associated with bilateral nasolacrimal duct obstruction (LCDD). [provided by RefSeq, Jun 2016]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO03203 IGSF3 Knockout cell line (HeLa) Human IGSF3 1:3~1:6 Negative Online Inquiry
KO03204 IGSF3 Knockout cell line (HCT 116) Human IGSF3 1:2~1:4 Negative Online Inquiry
KO03205 IGSF3 Knockout cell line (HEK293) Human IGSF3 1:3~1:6 Negative Online Inquiry
KO03206 IGSF3 Knockout cell line (A549) Human IGSF3 1:3~1:4 Negative Online Inquiry

Background

IGSF3 Gene Knockout Cell Lines are specially engineered cellular models where the Immunoglobulin Superfamily Member 3 (IGSF3) gene has been inactivated through advanced CRISPR-Cas9 technology. This innovative product allows researchers to explore the intricate biological mechanisms associated with IGSF3, which plays a critical role in cellular adhesion and signaling pathways. By utilizing these knockout cell lines, scientists can investigate the phenotypic consequences of IGSF3 deficiency, providing insights into its impact on cell growth, differentiation, and response to external stimuli.

The key function of IGSF3 is its involvement in the formation and maintenance of tight junctions between cells, which is vital for maintaining epithelial barrier integrity. In studying these knockout cell lines, researchers can elucidate the role of IGSF3 in various biological processes like tumorigenesis, inflammation, and immune responses, which are essential for the advancement of both basic and applied biomedical research.

The scientific importance of IGSF3 Gene Knockout Cell Lines is underscored by their applications in both research and clinical settings, particularly in cancer biology and autoimmune diseases. By enabling detailed studies on gene function and interaction networks, these cell lines serve as robust platforms for drug testing and the development of targeted therapies.

Compared to alternative models, the IGSF3 Gene Knockout Cell Lines provide a highly specific and reproducible method for achieving gene disruption. With a streamlined workflow and ease of use, researchers can generate pertinent data more rapidly, minimizing the variability often associated with traditional knockout techniques.

For researchers and clinicians seeking to deepen their understanding of cellular mechanisms or develop novel therapeutic strategies, IGSF3 Gene Knockout Cell Lines represent a powerful tool that enhances experimental rigor and precision. Our expertise in genetic engineering and cell line development ensures that these products adhere to the highest standards of quality and reliability, empowering scientific inquiry and discovery.

Please note that all services are for research use only. Not intended for any clinical use.

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