Gene: IFI30
Official Full Name: IFI30 lysosomal thiol reductaseprovided by HGNC
Gene Summary: The protein encoded by this gene is a lysosomal thiol reductase that at low pH can reduce protein disulfide bonds. The enzyme is expressed constitutively in antigen-presenting cells and induced by gamma-interferon in other cell types. This enzyme has an important role in MHC class II-restricted antigen processing. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO31872 | IFI30 Knockout cell line (HeLa) | Human | IFI30 | 1:3~1:6 | Negative | Online Inquiry |
KO31873 | IFI30 Knockout cell line (HCT 116) | Human | IFI30 | 1:2~1:4 | Negative | Online Inquiry |
KO31874 | IFI30 Knockout cell line (HEK293) | Human | IFI30 | 1:3~1:6 | Negative | Online Inquiry |
KO31875 | IFI30 Knockout cell line (A549) | Human | IFI30 | 1:3~1:4 | Negative | Online Inquiry |
IFI30 Gene Knockout Cell Lines are engineered cellular models specifically designed to study the immunological and cellular functions of the IFI30 gene, which encodes for an interferon-inducible protein known to play a significant role in regulating immune responses. These knockout cell lines effectively eliminate the expression of the IFI30 gene, allowing researchers to explore the biological ramifications of IFI30 deficiency in various cellular processes, including antigen presentation, cytokine production, and immune system regulation.
The key mechanism underlying the functionality of IFI30 Gene Knockout Cell Lines lies in the use of targeted gene editing technologies such as CRISPR/Cas9. This process generates precise deletions in the gene, leading to a complete loss of protein expression. Researchers can consequently assess how the absence of IFI30 impacts cellular behavior, immune signaling pathways, and interactions with other immune cells. The ability to study these pathways in a controlled environment provides invaluable insights relevant to autoimmune diseases, cancer immunotherapy, and infectious diseases.
Scientifically, the significance of these knockout models extends into both basic and applied research. In clinical settings, they serve as critical tools for understanding disease mechanisms, identifying potential therapeutic targets, and developing novel treatment strategies. By employing IFI30 Gene Knockout Cell Lines, researchers can unravel complex immune responses and test hypotheses that may translate into clinical advancements.
One unique advantage of using our IFI30 Gene Knockout Cell Lines is their rigorous validation, ensuring that the knockout is consistent and reliable across experiments. Compared to similar products, our cell lines are optimized for enhanced performance and reproducibility, making them ideal for downstream applications such as drug screening, mechanistic studies, or biomarker discovery.
For researchers and clinicians seeking to deepen their understanding of immune mechanisms and their implications in health and disease, these knockout cell lines are an invaluable asset. They offer a simplified yet powerful model to dissect the functions of IFI30 in a variety of biological contexts.
Our company is committed to delivering high-quality biological products that empower research and innovation. With years of expertise in gene editing technologies and cell line development, we provide products that meet the rigorous standards of scientific excellence, ensuring our customers achieve their research goals with confidence.
Please note that all services are for research use only. Not intended for any clinical use.
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