Gene: IFI27
Official Full Name: interferon alpha inducible protein 27provided by HGNC
Gene Summary: Enables several functions, including RNA polymerase II-specific DNA-binding transcription factor binding activity; identical protein binding activity; and lamin binding activity. Involved in several processes, including defense response to symbiont; protein K48-linked ubiquitination; and pyroptotic inflammatory response. Acts upstream of or within negative regulation of transcription by RNA polymerase II and regulation of protein export from nucleus. Located in mitochondrial membrane and nuclear inner membrane. Is active in mitochondrion. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO04011 | IFI27 Knockout cell line (HeLa) | Human | IFI27 | 1:3~1:6 | Negative | Online Inquiry |
KO04012 | IFI27 Knockout cell line (HCT 116) | Human | IFI27 | 1:2~1:4 | Negative | Online Inquiry |
KO04013 | IFI27 Knockout cell line (HEK293) | Human | IFI27 | 1:3~1:6 | Negative | Online Inquiry |
KO04014 | IFI27 Knockout cell line (A549) | Human | IFI27 | 1:3~1:4 | Negative | Online Inquiry |
IFI27 Gene Knockout Cell Lines are advanced biological tools designed to facilitate detailed studies in gene function and regulation. Specifically engineered to lack the Interferon-Inducible Protein 27 (IFI27), these knockout cell lines serve as an invaluable resource for researchers investigating the role of this gene in immune responses, cancer biology, and viral pathogenesis.
The primary function of IFI27 relates to the modulation of immune signaling pathways, particularly in response to viral infections. By utilizing these knockout cell lines, researchers can elucidate the downstream effects of IFI27 absence, providing insights into cellular processes such as apoptosis, signal transduction, and inflammatory responses. The cell lines are created using CRISPR/Cas9 technology, ensuring precise and efficient gene editing, which allows for reproducibility and reliability in subsequent experimental results.
The scientific importance of IFI27 Gene Knockout Cell Lines is underscored by their applications in both basic research and clinical settings. They are particularly valuable in preclinical studies aimed at developing therapeutic strategies for viral infections and immune-related diseases. Furthermore, these models can assist in drug discovery efforts by identifying potential targets for intervention in IFI27-associated pathways.
Compared to traditional cell lines, the uniqueness of our IFI27 knockout models lies in their specific genetic modification that allows for the exploration of the direct consequences of IFI27 deficiency. This targeted approach provides researchers with a clearer understanding of the gene's function, thereby enhancing the quality and interpretability of experimental data.
The value of these knockout cell lines to researchers and clinicians is profound, as they not only facilitate the examination of new hypotheses but also aid in the identification of biomarkers for disease progression and treatment efficacy. Knowledge derived from using our cell lines can lead to significant advancements in therapeutic development and enhancement of clinical outcomes.
As a leader in the field of biological product development, our company is dedicated to providing high-quality, innovative tools that empower scientists to push the boundaries of their research. With a focus on precision and reliability, we ensure that our products, including the IFI27 Gene Knockout Cell Lines, meet the rigorous standards required in cutting-edge scientific inquiry.
Please note that all services are for research use only. Not intended for any clinical use.
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