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HSPBAP1 Knockout Cell Lines

Gene: HSPBAP1

Official Full Name: HSPB1 associated protein 1provided by HGNC

Gene Summary: This gene encodes a protein that binds to one of the small heat shock proteins, specifically hsp27. Hsp27 is involved with cell growth and differentiation. This encoded protein was found to be abnormally expressed in patients with intractable epilepsy, although how brain function is affected remains unknown. [provided by RefSeq, Sep 2011]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO17047 HSPBAP1 Knockout cell line (HeLa) Human HSPBAP1 1:3~1:6 Negative Online Inquiry
KO17048 HSPBAP1 Knockout cell line (HCT 116) Human HSPBAP1 1:2~1:4 Negative Online Inquiry
KO17049 HSPBAP1 Knockout cell line (HEK293) Human HSPBAP1 1:3~1:6 Negative Online Inquiry
KO17050 HSPBAP1 Knockout cell line (A549) Human HSPBAP1 1:3~1:4 Negative Online Inquiry

Background

HSPBAP1 Gene Knockout Cell Lines are specialized cellular models engineered to lack the expression of the HSPBAP1 gene, which encodes for Heat Shock Protein B Assocaited Protein 1. These cell lines serve as powerful tools in biomedical research, enabling the detailed study of the gene's role in cellular stress responses and its implications in various pathological conditions. By eliminating HSPBAP1 expression, researchers can investigate the consequent physiological changes, gain insight into cellular resilience mechanisms, and assess the impact on cellular signaling pathways.

The primary function of HSPBAP1 involves its association with heat shock proteins, contributing to protein folding and protection against cellular stress. In knockout cell lines, the loss of HSPBAP1 can lead to altered stress response pathways, revealing critical insights into the mechanisms underlying neurodegeneration, cancer biology, and other diseases where protein aggregation is a concern. This knockout model provides a straightforward method for researchers to analyze the changes in cellular behavior in response to stressors, drug treatments, or genetic modifications.

The scientific significance of HSPBAP1 Gene Knockout Cell Lines is profound, particularly in the realms of molecular biology and translational research. They are invaluable for studying the pathophysiology of diseases linked to heat shock protein dysfunction, making them relevant in drug discovery and therapeutic development settings, such as cancer treatment or neurodegenerative disease therapies.

Compared to traditional wild-type cell lines, HSPBAP1 knockout models offer precise control over the expression of the target gene, enabling clean and unambiguous experimental outcomes. This specificity allows researchers to draw clearer conclusions about the gene's functions and interactions, reducing potential confounding variables.

For researchers and clinicians aiming to unlock the mysteries of cellular stress responses or explore therapeutic targets in challenging diseases, HSPBAP1 Gene Knockout Cell Lines provide unparalleled value. The capacity to observe the direct consequences of HSPBAP1 loss equips scientists with potent insights that can pave the way toward novel strategies and solutions in healthcare.

Our company boasts extensive expertise in the development of specialized biological products, ensuring that each HSPBAP1 Gene Knockout Cell Line is meticulously constructed and rigorously validated for research excellence.

Please note that all services are for research use only. Not intended for any clinical use.

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