Gene: HOXC13
Official Full Name: homeobox C13provided by HGNC
Gene Summary: This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXC genes located in a cluster on chromosome 12. The product of this gene may play a role in the development of hair, nail, and filiform papilla. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO37232 | HOXC13 Knockout cell line (HeLa) | Human | HOXC13 | 1:3~1:6 | Negative | Online Inquiry |
KO37233 | HOXC13 Knockout cell line (HCT 116) | Human | HOXC13 | 1:2~1:4 | Negative | Online Inquiry |
KO37234 | HOXC13 Knockout cell line (HEK293) | Human | HOXC13 | 1:3~1:6 | Negative | Online Inquiry |
KO37235 | HOXC13 Knockout cell line (A549) | Human | HOXC13 | 1:3~1:4 | Negative | Online Inquiry |
HOXC13 Gene Knockout Cell Lines are precisely engineered cellular models where the HOXC13 gene has been effectively disrupted using advanced genome-editing techniques, such as CRISPR-Cas9. This product allows researchers to study the phenotypic and molecular consequences of HOXC13 gene deletion in various biological contexts, particularly in the realms of developmental biology and cancer research.
The primary function of these knockout cell lines is to facilitate the exploration of HOXC13’s role in cellular processes, such as differentiation, proliferation, and gene expression regulation. By creating a loss-of-function model, researchers can elucidate the pathways influenced by HOXC13 and its contributions to tissue homeostasis and diseases. The mechanisms of action can be assessed through comparative studies of wild-type versus knockout cells, providing insights into gene-gene interactions and network dynamics that may underpin developmental abnormalities or oncogenesis.
In terms of scientific importance, HOXC13 has been implicated in various cancers and is crucial for proper hair follicle and limb development. Thus, these knockout cell lines serve as invaluable tools in both research and clinical settings, enabling the assessment of potential therapeutic targets aimed at modulating HOXC13-related pathways.
Comparatively, our HOXC13 Gene Knockout Cell Lines stand out due to their high efficiency of gene editing and robust validation, ensuring researchers have confidence in their outcomes. Unlike traditional knockout techniques that may exhibit incomplete gene disruption or off-target effects, our lines are rigorously verified for complete and specific gene knockout.
For researchers and clinicians focused on genetics, oncology, or regenerative medicine, the availability of reliable HOXC13 knockout models represents a significant advance in their toolkit for discovering novel treatments and understanding disease mechanisms. Our commitment to quality and precision in the creation of these cell lines reflects our expertise in biological products, positioning us as a trusted partner in advancing scientific discovery.
Please note that all services are for research use only. Not intended for any clinical use.
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