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HOXB6 Knockout Cell Lines

Gene: HOXB6

Official Full Name: homeobox B6provided by HGNC

Gene Summary: This gene is a member of the Antp homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development, including that of lung and skin, and has been localized to both the nucleus and cytoplasm. Altered expression of this gene or a change in the subcellular localization of its protein is associated with some cases of acute myeloid leukemia and colorectal cancer. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO37268 HOXB6 Knockout cell line (HeLa) Human HOXB6 1:3~1:6 Negative Online Inquiry
KO37269 HOXB6 Knockout cell line (HCT 116) Human HOXB6 1:2~1:4 Negative Online Inquiry
KO37270 HOXB6 Knockout cell line (HEK293) Human HOXB6 1:3~1:6 Negative Online Inquiry
KO37271 HOXB6 Knockout cell line (A549) Human HOXB6 1:3~1:4 Negative Online Inquiry

Background

HOXB6 Gene Knockout Cell Lines are specifically engineered cellular models that have had the HOXB6 gene systematically inactivated. This gene, part of the homeobox gene family, plays a pivotal role in regulating developmental processes, including limb formation and cellular differentiation. The creation of HOXB6 knockout cell lines allows researchers to elucidate the functions of this gene in various biological contexts, from embryonic development to pathogenesis in diseases such as cancer.

These cell lines function by utilizing CRISPR-Cas9 technology, effectively creating targeted mutations that disable HOXB6 expression. This precise gene editing approach allows researchers to analyze the resultant phenotypic changes, gene expression modifications, and signaling pathway alterations that occur when HOXB6 is absent. Consequently, these models serve as valuable tools for investigating gene function, dissecting complex biological pathways, and developing therapeutic strategies.

The significance of HOXB6 Gene Knockout Cell Lines in research and clinical settings is profound. They are instrumental in advancing our understanding of developmental biology and genetic regulation, and provide insights into disorders linked to aberrant HOXB6 activity. Moreover, these cell lines can assist in drug discovery processes by serving as a platform for testing therapeutic agents targeting HOXB6-related pathways.

What distinguishes our HOXB6 Gene Knockout Cell Lines from alternatives is their high specificity and reliability, coupled with an extensive validation process ensuring consistent performance across experiments. By offering cell lines that meet stringent quality control standards and providing comprehensive technical support, we enable researchers to efficiently explore the role of HOXB6 without the typical variability seen in less rigorously validated models.

For researchers and clinicians aiming to make impactful discoveries, the availability of HOXB6 Gene Knockout Cell Lines represents a critical advancement. These models not only facilitate innovative research but also pave the way for potential clinical applications that can lead to novel treatment modalities. Our company brings expertise in gene editing technologies and a commitment to delivering high-quality biological products, ensuring that you have trusted tools to advance scientific knowledge and therapeutic development.

Please note that all services are for research use only. Not intended for any clinical use.

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