Gene: HOXA2
Official Full Name: homeobox A2provided by HGNC
Gene Summary: In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. The encoded protein may be involved in the placement of hindbrain segments in the proper location along the anterior-posterior axis during development. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO37295 | HOXA2 Knockout cell line (HEK293) | Human | HOXA2 | 1:3~1:6 | Negative | Online Inquiry |
KO37296 | HOXA2 Knockout cell line (A549) | Human | HOXA2 | 1:3~1:4 | Negative | Online Inquiry |
HOXA2 Gene Knockout Cell Lines are sophisticated biological tools designed to facilitate the study of the HOXA2 gene's role in development, disease, and cellular function. By employing CRISPR-Cas9 technology, these knockout cell lines effectively disable the HOXA2 gene, allowing researchers to explore its contribution to various physiological and pathological processes without the confounding effects of gene function.
The primary function of HOXA2 Gene Knockout Cell Lines is to provide a controlled environment in which the absence of HOXA2 can be examined. HOXA2 plays a critical role in embryonic development and has been implicated in various cancers and congenital disorders. Researchers can utilize these cell lines to investigate gene regulatory networks, signaling pathways, and cellular behaviors, such as proliferation, differentiation, and apoptosis, resulting from HOXA2 inactivation. The knockout cell lines allow for deeper insight into gene function, providing a framework for both basic and translational research.
The scientific importance of HOXA2 Gene Knockout Cell Lines extends to multiple research domains, including developmental biology, oncology, and regenerative medicine. These cell lines serve as valuable models in drug discovery and genetic therapy studies, as they enable the validation of therapeutic targets and the assessment of drug efficacy in the absence of HOXA2.
Compared to existing alternatives, HOXA2 Gene Knockout Cell Lines offer unparalleled specificity and reliability. The targeted knockout achieved through CRISPR-Cas9 ensures precise gene inactivation without off-target effects that are common in traditional knockout methods. Furthermore, the availability of well-characterized cell lines enhances reproducibility and trust in experimental outcomes, making them an indispensable tool for both academic and industry settings.
Investing in HOXA2 Gene Knockout Cell Lines will accelerate your research endeavors, allowing you to uncover new mechanisms of action and therapeutic avenues. Understanding the nuances of HOXA2’s function through targeted studies not only enhances existing knowledge but can contribute to novel approaches in treating diseases related to its dysregulation.
With a commitment to high-quality biological products, our company leverages years of expertise in genetic engineering and cell line development to ensure that researchers have access to cutting-edge tools, such as HOXA2 Gene Knockout Cell Lines, to advance scientific discovery effectively.
Please note that all services are for research use only. Not intended for any clinical use.
If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.
There is no product in your cart. |
CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.