Gene: HOOK3
Official Full Name: hook microtubule tethering protein 3provided by HGNC
Gene Summary: Hook proteins are cytosolic coiled-coil proteins that contain conserved N-terminal domains, which attach to microtubules, and more divergent C-terminal domains, which mediate binding to organelles. The Drosophila Hook protein is a component of the endocytic compartment.[supplied by OMIM, Apr 2004]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO24892 | HOOK3 Knockout cell line (HeLa) | Human | HOOK3 | 1:3~1:6 | Negative | Online Inquiry |
KO24893 | HOOK3 Knockout cell line (HCT 116) | Human | HOOK3 | 1:2~1:4 | Negative | Online Inquiry |
KO24894 | HOOK3 Knockout cell line (HEK293) | Human | HOOK3 | 1:3~1:6 | Negative | Online Inquiry |
KO24895 | HOOK3 Knockout cell line (A549) | Human | HOOK3 | 1:3~1:4 | Negative | Online Inquiry |
HOOK3 Gene Knockout Cell Lines are engineered cellular models that provide researchers with a powerful tool for studying gene function, cellular mechanisms, and disease phenotypes. These cell lines have been specifically designed to facilitate the disruption of the HOOK3 gene, a critical component involved in various cellular processes including intracellular transport and signal transduction. By utilizing CRISPR-Cas9 technology, our HOOK3 Gene Knockout Cell Lines ensure efficient and precise gene editing, allowing researchers to investigate the role of HOOK3 in cellular dynamics and its implications in health and disease.
The key functions of HOOK3 revolve around its role in cytoskeletal organization and endosomal transport processes. By knocking out this gene, researchers can elucidate the impacts on cellular morphology, growth patterns, and intracellular trafficking pathways. Such insights are crucial for understanding the molecular basis of diseases that arise from cellular transport dysfunction, including neurodegenerative diseases and cancer.
From a scientific perspective, HOOK3 Gene Knockout Cell Lines have extensive applications in both research and clinical settings. Researchers can utilize these cell lines for drug discovery, genetic screening, and functional assays that assess the pathway disruptions caused by the absence of HOOK3. Furthermore, these models enable the development of targeted therapies aimed at rectifying transport-related defects, thus offering potential clinical impact.
What sets our HOOK3 Gene Knockout Cell Lines apart from other alternatives is their validated performance and reliability. Every batch undergoes comprehensive characterization to ensure consistent knockout efficacy and reproducibility, significantly reducing variability in experimental outcomes. Additionally, the ease of use and adaptability of these cell lines in various experimental setups allow researchers to seamlessly integrate them into their existing workflows.
Investing in HOOK3 Gene Knockout Cell Lines equips researchers and clinicians with invaluable resources to advance their studies and promote innovation in therapeutic development. Our company’s longstanding expertise in genetic manipulation and commitment to quality further ensures that you are supported by cutting-edge tools designed to propel scientific discovery and enhance therapeutic strategies.
Please note that all services are for research use only. Not intended for any clinical use.
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