Home / HDHD3 Knockout Cell Lines

HDHD3 Knockout Cell Lines

Gene: HDHD3

Official Full Name: haloacid dehalogenase like hydrolase domain containing 3provided by HGNC

Gene Summary: Predicted to enable hydrolase activity. Located in nucleolus. [provided by Alliance of Genome Resources, Apr 2025]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO25589 HDHD3 Knockout cell line (HeLa) Human HDHD3 1:3~1:6 Negative Online Inquiry
KO25590 HDHD3 Knockout cell line (HCT 116) Human HDHD3 1:2~1:4 Negative Online Inquiry
KO25591 HDHD3 Knockout cell line (HEK293) Human HDHD3 1:3~1:6 Negative Online Inquiry
KO25592 HDHD3 Knockout cell line (A549) Human HDHD3 1:3~1:4 Negative Online Inquiry

Background

HDHD3 Gene Knockout Cell Lines are specifically engineered cellular models that facilitate the study of HDHD3 gene function by creating a complete loss-of-function condition. By employing CRISPR-Cas9 technology, these cell lines eliminate the HDHD3 gene, which encodes a critical enzyme involved in the metabolism of certain fatty acids and phospholipids. The creation of these knockout models allows researchers to investigate the physiological and pathological roles that HDHD3 may play in various cellular processes, notably in lipid metabolism and cellular signaling pathways.

The key function of HDHD3 Gene Knockout Cell Lines lies in their ability to provide insight into the phenotype associated with the absence of HDHD3. Researchers can observe downstream effects on lipid accumulation, cell signaling, and overall cell health, thus revealing the molecular mechanisms underlying metabolic disorders and other diseases where HDHD3 dysfunction may be implicated. This innovative approach opens new avenues for understanding diseases such as obesity, diabetes, and certain types of cancer, where lipid dysregulation is a hallmark.

In clinical and research settings, HDHD3 Gene Knockout Cell Lines are invaluable for drug discovery and testing, enabling scientists to screen for compounds that could modulate the activity of the HDHD3 pathway. Compared to traditional methods, such as knockdown techniques or pharmacological inhibition, these knockout models deliver a complete gene function analysis, ensuring a more robust understanding of the gene's role. This makes them superior tools for experimental validation and translational research.

Furthermore, using HDHD3 Gene Knockout Cell Lines offers significant advantages: they demonstrate better specificity and reduced off-target effects compared to RNA interference methods. This precision leads to more reliable experimental outcomes, which are vital for developing targeted therapies.

For researchers and clinicians dedicated to the exploration of metabolic pathways and their implications in health and disease, these cell lines represent a cutting-edge resource. Our company brings decades of expertise in cellular model development, coupled with a commitment to advancing scientific research, ensuring that our HDHD3 Gene Knockout Cell Lines meet the rigorous demands of your research initiatives.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.