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H3C10 Knockout Cell Lines

Gene: H3C10

Official Full Name: H3 clustered histone 10provided by HGNC

Gene Summary: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the small histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq, Aug 2015]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO34237 H3C10 Knockout cell line (HeLa) Human H3C10 1:3~1:6 Negative Online Inquiry
KO34238 H3C10 Knockout cell line (HCT 116) Human H3C10 1:2~1:4 Negative Online Inquiry
KO34239 H3C10 Knockout cell line (HEK293) Human H3C10 1:3~1:6 Negative Online Inquiry
KO34240 H3C10 Knockout cell line (A549) Human H3C10 1:3~1:4 Negative Online Inquiry

Background

H3C10 Gene Knockout Cell Lines are specialized cellular models engineered to lack the expression of the H3C10 gene. This innovative genetic manipulation technique allows researchers to study the functional role of H3C10 in various biological processes, including cell growth, differentiation, and response to therapeutic agents. By utilizing CRISPR-Cas9 technology, our H3C10 Knockout Cell Lines have been precisely edited to ensure the reproducibility and specificity necessary for rigorous scientific inquiry.

These cell lines are invaluable tools in both basic and applied research. They enable scientists to elucidate the mechanisms by which H3C10 influences cellular behavior, such as metabolic pathways or signal transduction cascades. In clinical settings, these models are particularly important for drug discovery and development, providing insight into therapeutic efficacy and potential side effects, ultimately accelerating the translation of laboratory findings to clinical applications.

What sets our H3C10 Gene Knockout Cell Lines apart from competitors is our commitment to quality and validation. Each batch is thoroughly characterized to confirm knockout efficiency and phenotypic stability, ensuring that researchers can depend on consistent results across experiments. Additionally, we offer comprehensive support and resources, including detailed protocols and guidance for optimization, making it easier for scientists to integrate these models into their workflows.

For researchers and clinicians, the H3C10 Gene Knockout Cell Lines represent an essential resource that enhances experimental validity and extends the possibilities of scientific exploration. Our company brings over a decade of expertise in genotyping and gene editing technologies, fostering innovation and supporting cutting-edge research that drives advancements in biomedical science.

Please note that all services are for research use only. Not intended for any clinical use.

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