Gene: H2BC21
Official Full Name: H2B clustered histone 21provided by HGNC
Gene Summary: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-dependent histone that is a member of the histone H2B family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. The protein has antibacterial and antifungal antimicrobial activity. [provided by RefSeq, Aug 2015]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO06549 | H2BC21 Knockout cell line (HeLa) | Human | H2BC21 | 1:3~1:6 | Negative | Online Inquiry |
KO06550 | H2BC21 Knockout cell line (HEK293) | Human | H2BC21 | 1:3~1:6 | Negative | Online Inquiry |
KO06551 | H2BC21 Knockout cell line (A549) | Human | H2BC21 | 1:3~1:4 | Negative | Online Inquiry |
H2BC21 Gene Knockout Cell Lines are genetically engineered cell lines designed to facilitate the study of gene function and regulation by providing a model in which the specific H2BC21 gene is completely disrupted. By employing advanced CRISPR-Cas9 technology, these cell lines effectively illustrate the impact of H2BC21 deletion on cellular processes, allowing researchers to delve deeper into its role in various biological pathways.
The functionality of H2BC21 gene knockout cell lines rests on their ability to permit researchers to observe the phenotypic and molecular changes that occur when the expression of the H2BC21 gene is absent. This enables detailed examinations of cellular responses, signaling pathways, and gene interactions, making them an indispensable resource for elucidating the gene’s contribution to processes such as cell cycle regulation, differentiation, and stress responses.
The scientific significance of H2BC21 gene knockout cell lines extends into both basic research and potential therapeutic development. They are exceptionally valuable in studying diseases where H2BC21 plays a pivotal role, including various types of cancer and genetic disorders. Their predictive capabilities in preclinical models can accelerate the identification of drug targets and therapeutic interventions.
Compared to traditional cell line models, H2BC21 gene knockout cell lines offer enhanced specificity and reproducibility. They are rigorously validated for gene disruption, ensuring that researchers obtain reliable and consistent data. Furthermore, their streamlined application process and compatibility with high-throughput screening make them a superior choice amidst conventional alternatives.
This product is pivotal for researchers and clinicians aiming to unravel complex biological systems and forge new paths in therapeutic discovery. With our extensive background in genetic engineering and cellular biology, we provide high-quality H2BC21 gene knockout cell lines that meet the rigorous demands of scientific exploration and innovation. Our commitment to excellence ensures that you are equipped with invaluable tools for your research or clinical applications.
Please note that all services are for research use only. Not intended for any clinical use.
If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.
There is no product in your cart. |
CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.