Gene: H1-10
Official Full Name: H1.10 linker histoneprovided by HGNC
Gene Summary: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent histone that is a member of the histone H1 family. [provided by RefSeq, Oct 2015]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO33690 | H1-10 Knockout cell line (HeLa) | Human | H1-10 | 1:3~1:6 | Negative | Online Inquiry |
KO33691 | H1-10 Knockout cell line (HCT 116) | Human | H1-10 | 1:2~1:4 | Negative | Online Inquiry |
KO33692 | H1-10 Knockout cell line (HEK293) | Human | H1-10 | 1:3~1:6 | Negative | Online Inquiry |
KO33693 | H1-10 Knockout cell line (A549) | Human | H1-10 | 1:3~1:4 | Negative | Online Inquiry |
H1-10 Gene Knockout Cell Lines are specialized engineered cellular models designed to facilitate the analysis of gene function through the systematic disruption of the H1-10 gene. These cell lines are created using advanced CRISPR/Cas9 gene editing technology, which enables precise deletion or alteration of specific gene sequences, resulting in a loss-of-function phenotype. By effectively silencing the H1-10 gene, researchers can study the biological pathways influenced by this gene, uncovering its role in various cellular processes, including regulation of cell proliferation, differentiation, and response to stimuli.
The key function of H1-10 Gene Knockout Cell Lines lies in their ability to mimic disease states or specific biological conditions, making them invaluable tools for investigating gene function in a controlled environment. In vitro experiments using these cell lines can reveal critical insights into disease mechanisms, drug interactions, and genetic interactions, significantly advancing our understanding of complex biological systems.
Scientifically, H1-10 Gene Knockout Cell Lines have a wide range of applications in both research and clinical settings. They can be employed for drug discovery, toxicology studies, and the development of gene therapies, enabling researchers to explore therapeutic targets associated with the H1-10 gene. Additionally, these cell lines offer promising models for studying various cancers, metabolic disorders, and other pathologies linked to gene dysregulation.
Compared to traditional models, H1-10 Gene Knockout Cell Lines provide enhanced specificity and reproducibility, allowing for a more accurate interpretation of experimental data. Their ease of use and scalability offer researchers the ability to conduct high-throughput screenings, which can expedite the screening of new therapeutic compounds.
For researchers and clinicians striving for precision in genetic studies and therapeutic innovations, H1-10 Gene Knockout Cell Lines represent a valuable addition to their toolkit. With the combined expertise and commitment to quality that our company offers, we ensure that these cell lines meet rigorous scientific standards, empowering users to achieve groundbreaking discoveries in the field of molecular biology and genetics.
Please note that all services are for research use only. Not intended for any clinical use.
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