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GZF1 Knockout Cell Lines

Gene: GZF1

Official Full Name: GDNF inducible zinc finger protein 1provided by HGNC

Gene Summary: Enables DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II. Located in nucleolus and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO17210 GZF1 Knockout cell line (HeLa) Human GZF1 1:3~1:6 Negative Online Inquiry
KO17211 GZF1 Knockout cell line (HCT 116) Human GZF1 1:2~1:4 Negative Online Inquiry
KO17212 GZF1 Knockout cell line (HEK293) Human GZF1 1:3~1:6 Negative Online Inquiry
KO17213 GZF1 Knockout cell line (A549) Human GZF1 1:3~1:4 Negative Online Inquiry

Background

GZF1 Gene Knockout Cell Lines are specialized cellular models created through the targeted deletion of the GZF1 gene, an essential component in various physiological and pathological processes. By utilizing advanced CRISPR-Cas9 gene-editing technology, these cell lines enable researchers to explore the functional role of GZF1 in cellular mechanisms, such as metabolic regulation, immune response modulation, and transcriptional control. The knockout of this gene provides a valuable tool for dissecting its contributions to disease states, including cancer and metabolic disorders, thereby fostering a deeper understanding of its biological significance.

The GZF1 gene is known to influence several signaling pathways that are critical for cell growth and differentiation. By observing the phenotypic changes that arise from the GZF1 knockout, researchers can gain insights into cellular pathways and their implications in health and disease. Additionally, these cell lines are highly reproducible and standardized, which supports their application in high-throughput screenings and drug discovery, offering a reliable platform for pharmacological manipulation and therapeutic intervention studies.

Compared to conventional knockdown techniques, such as RNA interference, the GZF1 Gene Knockout Cell Lines provide a more stable and complete elimination of gene function, ensuring that any observed biological effects are a direct result of GZF1 loss rather than residual activity. This specificity enhances data interpretation and provides a clearer understanding of gene function.

Designed for both research and clinical laboratories, these cell lines are essential for scientists seeking to unravel complex genetic interactions and identify novel therapeutic targets. Their robustness and ease of use make them an indispensable asset for researchers focused on genetics, cell biology, and therapeutic development.

With a strong commitment to advancing biological research, our company has invested extensively in the development and refinement of these knockout models, ensuring that they meet the highest standards of quality and reliability in the field. Our expertise in gene editing and cell line development positions us to support your research goals with innovative, state-of-the-art biological products.

Please note that all services are for research use only. Not intended for any clinical use.

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