Gene: GRSF1
Official Full Name: G-rich RNA sequence binding factor 1provided by HGNC
Gene Summary: The protein encoded by this gene is a cellular protein that binds RNAs containing the G-rich element. The protein is localized in the cytoplasm, and has been shown to stimulate translation of viral mRNAs in vitro. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO37492 | GRSF1 Knockout cell line (HeLa) | Human | GRSF1 | 1:3~1:6 | Negative | Online Inquiry |
KO37493 | GRSF1 Knockout cell line (HCT 116) | Human | GRSF1 | 1:2~1:4 | Negative | Online Inquiry |
KO37494 | GRSF1 Knockout cell line (HEK293) | Human | GRSF1 | 1:3~1:6 | Negative | Online Inquiry |
KO37495 | GRSF1 Knockout cell line (A549) | Human | GRSF1 | 1:3~1:4 | Negative | Online Inquiry |
GRSF1 Gene Knockout Cell Lines are specially engineered cellular models in which the GRSF1 gene has been intentionally disrupted or "knocked out." GRSF1 (G-rich RNA sequence binding factor 1) is known to play a critical role in RNA metabolism and regulation, particularly in the expression and stability of mRNA. By utilizing CRISPR-Cas9 or other gene-editing technologies, these cell lines facilitate targeted studies of gene function and the pathological implications of GRSF1 dysregulation.
The primary mechanism of action of the GRSF1 gene knockout involves the loss of the protein product associated with the GRSF1 gene, leading to downstream effects on various cellular processes, including translation regulation and RNA splicing. By studying these knockout cell lines, researchers can elucidate the biological roles of GRSF1 in cellular homeostasis, cancer progression, and other diseases, offering deeper insights into potential therapeutic targets.
The scientific significance of GRSF1 Gene Knockout Cell Lines lies in their ability to serve as a powerful tool for both basic and applied research. In clinical settings, these lines can help in the development of novel gene therapies or in the identification of biomarkers for diseases where GRSF1 is implicated. Furthermore, as GRSF1 has been linked to the modulation of stress responses and cellular aging, understanding its pathways could lead to breakthroughs in regenerative medicine.
Compared to traditional gene editing approaches that may produce off-target effects, our GRSF1 Gene Knockout Cell Lines offer precision and reproducibility, ensuring that researchers can confidently interpret their data. Moreover, the availability of these knockout models significantly reduces the time and resources needed to create custom gene-edited cell lines, streamlining research efforts.
For researchers, clinicians, and biotechnology companies interested in unraveling the complexities of gene function and pathology, GRSF1 Gene Knockout Cell Lines provide an invaluable resource. Our company is dedicated to delivering high-quality biological reagents and cell models, underpinned by extensive expertise in genetics and cell biology, ensuring that your research is supported by the best tools available in the field.
Please note that all services are for research use only. Not intended for any clinical use.
If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.
There is no product in your cart. |
CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.