Gene: GPR108
Official Full Name: G protein-coupled receptor 108provided by HGNC
Gene Summary: Predicted to be involved in negative regulation of toll-like receptor signaling pathway. Located in trans-Golgi network. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO03682 | GPR108 Knockout cell line (HeLa) | Human | GPR108 | 1:3~1:6 | Negative | Online Inquiry |
KO03683 | GPR108 Knockout cell line (HCT 116) | Human | GPR108 | 1:2~1:4 | Negative | Online Inquiry |
KO03684 | GPR108 Knockout cell line (HEK293) | Human | GPR108 | 1:3~1:6 | Negative | Online Inquiry |
KO03685 | GPR108 Knockout cell line (A549) | Human | GPR108 | 1:3~1:4 | Negative | Online Inquiry |
GPR108 Gene Knockout Cell Lines are specialized cellular models engineered to lack the expression of the GPR108 gene, which encodes a G protein-coupled receptor known to play crucial roles in various physiological processes. These knockout cell lines are vital tools for investigating the functional roles of GPR108 in cellular signaling pathways, understanding disease mechanisms, and developing therapeutic strategies.
The key functions of GPR108 typically link to processes such as immune response modulation and cell proliferation. By utilizing these knockout cell lines, researchers can elucidate the receptor’s contributions to pathophysiological conditions, including cancer and autoimmune diseases, as they permit the observation of changes in biochemical pathways that occur in the absence of GPR108 expression.
The scientific importance of GPR108 Gene Knockout Cell Lines extends to both basic and translational research. They provide a reliable platform for studying receptor signaling in a controlled environment, allowing for more accurate interpretations of data when developing receptor-targeted therapeutics. These models are also invaluable in drug discovery and screening processes, enabling scientists to identify compounds that can modulate the GPR108 pathway.
What sets GPR108 Gene Knockout Cell Lines apart from traditional cell lines is their specific genetic alteration, which allows for targeted studies of the receptor’s function without the confounding effects of gene expression. The unique selling points include their high specificity, consistent performance, and the ability to perform various assays, such as Western blotting, flow cytometry, and functional assays, to assess cellular responses reliably.
These cell lines represent a significant advancement for researchers and clinicians by paving the way for breakthroughs in understanding GPR108-related biological processes. Their adaptability and precision make them indispensable for those seeking to drive forward research into novel therapeutic approaches.
Our company specializes in providing high-quality biological products tailored to advanced research needs. With expertise in cellular models and genetic engineering, we are committed to supporting scientific discovery through innovative solutions like the GPR108 Gene Knockout Cell Lines.
Please note that all services are for research use only. Not intended for any clinical use.
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