Gene: GOPC
Official Full Name: golgi associated PDZ and coiled-coil motif containingprovided by HGNC
Gene Summary: This gene encodes a Golgi protein with a PDZ domain. The PDZ domain is globular and proteins which contain them bind other proteins through short motifs near the C-termini. Mice which are deficient in the orthologous protein have globozoospermia and are infertile. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO17331 | GOPC Knockout cell line (HeLa) | Human | GOPC | 1:3~1:6 | Negative | Online Inquiry |
KO17332 | GOPC Knockout cell line (HCT 116) | Human | GOPC | 1:2~1:4 | Negative | Online Inquiry |
KO17333 | GOPC Knockout cell line (HEK293) | Human | GOPC | 1:3~1:6 | Negative | Online Inquiry |
KO17334 | GOPC Knockout cell line (A549) | Human | GOPC | 1:3~1:4 | Negative | Online Inquiry |
GOPC Gene Knockout Cell Lines are genetically engineered cell lines specifically designed to lack the GOPC gene, which is implicated in various cellular processes including Golgi apparatus function and cellular signaling pathways. By creating these knockout models, researchers can investigate the physiological and pathological roles of GOPC in a controlled environment, allowing for a more profound understanding of its contributions to cellular mechanisms and disease states.
The primary function of these cell lines is to provide a platform for examining the effects of the absence of GOPC on gene expression, protein interactions, and cellular behavior. Mechanistically, the knockout of the GOPC gene can disrupt normal protein trafficking and cellular signaling, thus enabling scientists to study the downstream effects associated with its loss. Such insights are pivotal, particularly in conditions where GOPC has been correlated with diseases such as cancer and neurodegenerative disorders.
The scientific importance of GOPC Gene Knockout Cell Lines extends to both research and clinical settings, serving as invaluable tools for drug discovery and validation of therapeutic targets. They allow for high-throughput screening of compounds that may restore normal function or exhibit specificity in targeting cells with altered GOPC expression. This capability dramatically enhances the speed and efficiency of translational research, making this product particularly valuable in the rapidly evolving field of biomedical research.
One of the key advantages of the GOPC Gene Knockout Cell Lines compared to traditional cell lines is their ability to simulate disease conditions more accurately, offering researchers a model that closely resembles human pathophysiology. Furthermore, these knockout lines are rigorously validated and characterized, ensuring reliability in experimental outcomes, which is often lacking in alternative models.
For researchers and clinicians invested in understanding Golgi apparatus functions or exploring pathways associated with GOPC, these cell lines represent a cutting-edge resource. Their unique characteristics not only facilitate advanced research but also help expedite the development of novel therapeutic strategies.
Our company prides itself on being at the forefront of genetic engineering, providing high-quality biological products that cater to the diverse needs of the scientific community. With expertise in gene manipulation and a commitment to innovation, we offer tools like the GOPC Gene Knockout Cell Lines that empower researchers to unlock new discoveries in health and disease.
Please note that all services are for research use only. Not intended for any clinical use.
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