Gene: GOLGA3
Official Full Name: golgin A3provided by HGNC
Gene Summary: The Golgi apparatus, which participates in glycosylation and transport of proteins and lipids in the secretory pathway, consists of a series of stacked cisternae (flattened membrane sacs). Interactions between the Golgi and microtubules are thought to be important for the reorganization of the Golgi after it fragments during mitosis. This gene encodes a member of the golgin family of proteins which are localized to the Golgi. Its encoded protein has been postulated to play a role in nuclear transport and Golgi apparatus localization. Several alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Feb 2010]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO37579 | GOLGA3 Knockout cell line (HeLa) | Human | GOLGA3 | 1:3~1:6 | Negative | Online Inquiry |
KO37580 | GOLGA3 Knockout cell line (HCT 116) | Human | GOLGA3 | 1:2~1:4 | Negative | Online Inquiry |
KO37581 | GOLGA3 Knockout cell line (HEK293) | Human | GOLGA3 | 1:3~1:6 | Negative | Online Inquiry |
KO37582 | GOLGA3 Knockout cell line (A549) | Human | GOLGA3 | 1:3~1:4 | Negative | Online Inquiry |
GOLGA3 Gene Knockout Cell Lines are genetically modified cell lines in which the GOLGA3 gene has been inactivated, allowing researchers to define the functional implications of this specific gene in cellular processes. The GOLGA3 gene encodes for a protein involved in Golgi apparatus structure and function, contributing to intracellular transport, protein maturation, and overall cell viability. By utilizing these knockout cell lines, scientists can investigate the role of GOLGA3 in various biological processes and diseases, including cancer and metabolic disorders.
The key functionality of GOLGA3 Gene Knockout Cell Lines lies in their ability to elucidate the gene's role through loss-of-function studies. By observing the phenotypic and molecular changes that occur when GOLGA3 is disrupted, researchers can gain insights into its contribution to cellular pathways, protein interactions, and responses to external stimuli. This functional assessment helps clarify the mechanisms through which GOLGA3 may influence disease progression and cellular homeostasis.
Scientifically, GOLGA3 Gene Knockout Cell Lines serve as invaluable tools in both basic and applied research. In clinical settings, these cell lines can expedite drug discovery initiatives, as they allow for the examination of therapeutic targets related to the GOLGA3 protein. Additionally, they contribute to the understanding of Golgi-related diseases and conditions linked to cellular transport dysfunction.
The unique selling points of our GOLGA3 Gene Knockout Cell Lines include their high specificity and reproducibility, verified by stringent quality control protocols. Unlike other alternative models, our cell lines ensure that alterations related to GOLGA3 are exclusively due to knockout rather than confounding factors, providing a reliable platform for experimental investigations.
For researchers and clinicians focused on molecular biology and disease mechanisms, GOLGA3 Gene Knockout Cell Lines represent a significant advancement, enabling innovative research that informs therapeutic development. Our company prides itself on delivering high-quality biological products backed by years of expertise in genetic engineering and cell culture technology, ensuring that scientists have access to reliable and effective research tools.
Please note that all services are for research use only. Not intended for any clinical use.
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