Home / GMCL1 Knockout Cell Lines

GMCL1 Knockout Cell Lines

Gene: GMCL1

Official Full Name: germ cell-less 1, spermatogenesis associatedprovided by HGNC

Gene Summary: This gene encodes a nuclear envelope protein that appears to be involved in spermatogenesis, either directly or by influencing genes that play a more direct role in the process. This multi-exon locus is the homolog of the mouse and drosophila germ cell-less gene but the human genome also contains a single-exon locus on chromosome 5 that contains an open reading frame capable of encoding a highly-related protein. [provided by RefSeq, Jul 2008]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO20779 GMCL1 Knockout cell line (HeLa) Human GMCL1 1:3~1:6 Negative Online Inquiry
KO20780 GMCL1 Knockout cell line (HCT 116) Human GMCL1 1:2~1:4 Negative Online Inquiry
KO20781 GMCL1 Knockout cell line (HEK293) Human GMCL1 1:3~1:6 Negative Online Inquiry
KO20782 GMCL1 Knockout cell line (A549) Human GMCL1 1:3~1:4 Negative Online Inquiry

Background

GMCL1 Gene Knockout Cell Lines are genetically engineered human cell lines that have undergone targeted mutagenesis to disrupt the GMCL1 gene. This innovative product allows researchers to delve deeper into the functional role of GMCL1 in various biological processes, particularly those related to cellular differentiation and immune responses. By completely knocking out the GMCL1 gene, these cell lines provide a powerful tool for studying gene function and its implications in disease pathogenesis.

The key mechanism underlying the functionality of GMCL1 Gene Knockout Cell Lines lies in the complete absence of GMCL1 protein expression. Researchers can use these knockout models to observe phenotypic changes and to evaluate downstream signaling pathways and gene expression profiles that may occur as a result of the gene's loss. This allows for a more comprehensive understanding of cellular mechanisms in both normal and disease states.

In terms of scientific importance, these knockout cell lines have wide applications in biomedical research. They are particularly valuable in studies focused on cancer, autoimmune diseases, and developmental biology. By enhancing our understanding of GMCL1’s role, these models can facilitate the development of targeted therapies and interventions.

Compared to wild-type cell lines or other gene-editing methods, GMCL1 Gene Knockout Cell Lines provide an unparalleled level of specificity and reproducibility in terms of gene disruption. They eliminate potential off-target effects, ensuring that observed effects are directly related to the absence of the GMCL1 gene.

For researchers and clinicians, the availability of GMCL1 Gene Knockout Cell Lines represents a significant advancement in their investigative toolkit, offering reliable methods to explore critical biological questions and therapeutic strategies. Our company is dedicated to providing high-quality, well-characterized biological products backed by extensive scientific research, positioning us as an essential partner in advancing your research and clinical endeavors.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.