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GLYR1 Knockout Cell Lines

Gene: GLYR1

Official Full Name: glyoxylate reductase 1 homologprovided by HGNC

Gene Summary: Enables several functions, including chromatin-protein adaptor activity; methylated histone binding activity; and nucleosome binding activity. Involved in transcription elongation-coupled chromatin remodeling and transcription initiation-coupled chromatin remodeling. Located in cytosol and nucleoplasm. Part of nucleosome. Is active in chromatin. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO05248 GLYR1 Knockout cell line (HeLa) Human GLYR1 1:3~1:6 Negative Online Inquiry
KO05249 GLYR1 Knockout cell line (HCT 116) Human GLYR1 1:2~1:4 Negative Online Inquiry
KO05250 GLYR1 Knockout cell line (HEK293) Human GLYR1 1:3~1:6 Negative Online Inquiry
KO05251 GLYR1 Knockout cell line (A549) Human GLYR1 1:3~1:4 Negative Online Inquiry

Background

GLYR1 Gene Knockout Cell Lines represent a powerful tool in molecular biology, specifically designed to elucidate the role of the GLYR1 gene in various physiological and pathological processes. These engineered cell lines are produced by utilizing CRISPR-Cas9 technology to create a specific knockout of the GLYR1 gene, allowing researchers to investigate the gene's contributions to cellular function without its influence.

The primary mechanism of action involves the targeted disruption of the gene, leading to the absence of the GLYR1 protein. This absence can significantly alter various cellular pathways, including energy metabolism, stress response, and cellular signaling pathways. As such, these knockout cell lines serve as invaluable models for dissecting the gene’s biological function and understanding its implications in diseases like cancer and metabolic disorders.

In terms of scientific importance, GLYR1 Gene Knockout Cell Lines are crucial in both research and clinical settings. They provide insight into the gene’s potential role as a biomarker for disease progression or treatment response, and can support drug discovery initiatives aimed at targeting related pathways. Furthermore, by facilitating a more profound exploration of GLYR1's function, these cell lines can accelerate translational research efforts that might lead to novel therapeutic options.

Compared to traditional cell lines, the specific knockout of the GLYR1 gene allows for more precise investigations, minimizing confounding factors by eliminating variable gene expression. This specificity affords researchers greater control over experimental conditions, enabling more reproducible and reliable results.

For researchers and clinicians looking to gain deeper insights into the GLYR1 gene, these knockout cell lines offer a pragmatic choice for experimental design, laying the groundwork for innovative research. Leveraging years of expertise in the field of molecular biology and genetic engineering, our company is dedicated to providing high-quality biological products that empower scientific discovery and foster advancements in healthcare.

Please note that all services are for research use only. Not intended for any clinical use.

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