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GID8 Knockout Cell Lines

Gene: GID8

Official Full Name: GID complex subunit 8 homologprovided by HGNC

Gene Summary: Predicted to enable protein homodimerization activity. Involved in positive regulation of canonical Wnt signaling pathway and positive regulation of cell population proliferation. Located in cell junction; cytosol; and nucleoplasm. Part of ubiquitin ligase complex. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO17386 GID8 Knockout cell line (HeLa) Human GID8 1:3~1:6 Negative Online Inquiry
KO17387 GID8 Knockout cell line (HCT 116) Human GID8 1:2~1:4 Negative Online Inquiry
KO17388 GID8 Knockout cell line (HEK293) Human GID8 1:3~1:6 Negative Online Inquiry
KO17389 GID8 Knockout cell line (A549) Human GID8 1:3~1:4 Negative Online Inquiry

Background

GID8 Gene Knockout Cell Lines are specialized mammalian cell lines that have been genetically engineered to inactivate the GID8 gene, which is implicated in various biological pathways including cellular metabolism, transcription regulation, and developmental processes. This innovative tool allows researchers to dissect the specific roles and mechanisms of GID8 within the context of cellular function and disease. Utilizing CRISPR/Cas9 technology, these cell lines precisely edit the GID8 gene, creating a reliable and reproducible model for gene function studies.

The primary function of the GID8 knockout cell lines lies in their ability to facilitate the exploration of GID8’s role in key signaling pathways, thereby enabling scientists to investigate downstream effects on gene expression, cellular growth, and response to stressors. This understanding has significant implications not only for fundamental biological research but also for translational applications in fields such as oncology, metabolic disorders, and regenerative medicine. Researchers are empowered to uncover potential therapeutic targets and biomarkers associated with the aberrant function of GID8, driving forward advancements in personalized medicine.

What sets GID8 Gene Knockout Cell Lines apart from other gene editing products is their high specificity and efficiency in gene disruption, coupled with excellent cell viability post-manipulation. Unlike other knockout systems that may generate off-target effects or have variable outcomes, GID8 knockout lines provide consistent performance for experimental reproducibility, making them an indispensable resource for clinical and academic laboratories alike.

The value of these cell lines extends to both researchers and clinicians, as they provide a platform to develop targeted gene therapies and improve our understanding of disease mechanisms. By employing GID8 knockout cell lines, users are equipped with a powerful tool that enhances the depth and quality of their research findings.

Our company boasts considerable expertise in the development of cutting-edge genetic products and is committed to supporting scientific innovation. With a focus on high-quality and reliable cell lines, we empower researchers with the tools they need to advance their work—maximizing the impact of their findings in the vast landscape of biological research.

Please note that all services are for research use only. Not intended for any clinical use.

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