Gene: GFUS
Official Full Name: GDP-L-fucose synthaseprovided by HGNC
Gene Summary: Tissue specific transplantation antigen P35B is a NADP(H)-binding protein. It catalyze the two-step epimerase and the reductase reactions in GDP-D-mannose metabolism, converting GDP-4-keto-6-D-deoxymannose to GDP-L-fucose. GDP-L-fucose is the substrate of several fucosyltransferases involved in the expression of many glycoconjugates, including blood group ABH antigens and developmental adhesion antigens. Mutations in this gene may cause leukocyte adhesion deficiency, type II. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO34916 | GFUS Knockout cell line (HeLa) | Human | GFUS | 1:3~1:6 | Negative | Online Inquiry |
KO34917 | GFUS Knockout cell line (HCT 116) | Human | GFUS | 1:2~1:4 | Negative | Online Inquiry |
KO34918 | GFUS Knockout cell line (HEK293) | Human | GFUS | 1:3~1:6 | Negative | Online Inquiry |
KO34919 | GFUS Knockout cell line (A549) | Human | GFUS | 1:3~1:4 | Negative | Online Inquiry |
GFUS Gene Knockout Cell Lines are innovative biological tools designed to facilitate the functional analysis of specific genes within cellular contexts. These cell lines are engineered using advanced CRISPR/Cas9 technology, which allows for precise and efficient gene editing to create knockout models that lack the expression of targeted genes. This precision enables researchers to dissect the role of genes in various biological processes, offering insights that can lead to breakthroughs in understanding cellular mechanisms underlying diseases.
The primary function of GFUS Gene Knockout Cell Lines lies in their ability to model gene loss-of-function scenarios, allowing for in-depth investigations into gene function, protein interactions, and signaling pathways. By systematically examining the phenotypic consequences of gene disruption, researchers can elucidate the biological relevance of genes in both normal physiology and pathological conditions, such as cancer, neurodegenerative diseases, and genetic disorders.
The scientific importance of GFUS Cell Lines is underscored by their diverse applications in research and clinical settings. They serve as invaluable tools for drug development, genetic screens, and functional genomics studies. Utilizing these knockout models enables the identification of potential therapeutic targets and the validation of candidates in preclinical studies, thereby accelerating the translational potential of findings from bench to bedside.
Compared to alternative gene editing approaches, GFUS Gene Knockout Cell Lines offer several unique advantages: they are rigorously validated for efficiency and specificity, are compatible with various genetic backgrounds, and provide a consistent, reproducible platform for experimentation. Furthermore, these cell lines are ready-to-use and come with comprehensive support, reducing the time and resources needed for researchers to establish their own models.
In summary, GFUS Gene Knockout Cell Lines represent a powerful asset for researchers and clinicians seeking to deepen their understanding of gene function and its implications in health and disease. Our company stands at the forefront of gene editing technologies, committed to providing high-quality biological products designed to advance scientific discovery and enhance research capabilities.
Please note that all services are for research use only. Not intended for any clinical use.
If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.
There is no product in your cart. |
CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.