Gene: GFPT2
Official Full Name: glutamine-fructose-6-phosphate transaminase 2provided by HGNC
Gene Summary: Enables glutamine-fructose-6-phosphate transaminase (isomerizing) activity. Involved in UDP-N-acetylglucosamine biosynthetic process and fructose 6-phosphate metabolic process. Predicted to be located in cytosol. Implicated in type 2 diabetes mellitus. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO32452 | GFPT2 Knockout cell line (HeLa) | Human | GFPT2 | 1:3~1:6 | Negative | Online Inquiry |
KO32453 | GFPT2 Knockout cell line (HCT 116) | Human | GFPT2 | 1:2~1:4 | Negative | Online Inquiry |
KO32454 | GFPT2 Knockout cell line (HEK293) | Human | GFPT2 | 1:3~1:6 | Negative | Online Inquiry |
KO32455 | GFPT2 Knockout cell line (A549) | Human | GFPT2 | 1:3~1:4 | Negative | Online Inquiry |
GFPT2 Gene Knockout Cell Lines represent a revolutionary tool in the field of molecular biology, specifically designed to facilitate the investigation of GFPT2 gene functions and its implications in various diseases. GFPT2 (Glutamine Fructose-6-Phosphate Transaminase 2) is a crucial enzyme involved in the hexosamine biosynthetic pathway, influencing cellular metabolism and signaling. By utilizing CRISPR/Cas9 technology, these knockout cell lines allow researchers to create a complete absence of GFPT2 expression, providing a unique model to study the downstream effects of its loss on cellular processes and metabolic pathways.
The primary function of the GFPT2 gene knockout cell lines is to serve as a reliable and accurate model to elucidate the role of GFPT2 in cellular homeostasis, as well as its contributions to pathological states like cancer and diabetes. By analyzing the behavior of these knockout cells, scientists can observe changes in glycosylation, apoptosis, and cellular proliferation, thereby gaining insights into the molecular mechanisms underlying GFPT2-related diseases.
These cell lines have significant applications in both research and clinical settings. They enable researchers to perform high-throughput screening for drug discovery and assess the metabolic reprogramming linked to GFPT2 activity. Clinically, comprehending GFPT2's role opens potential avenues for therapeutics targeting metabolic diseases and cancer.
What sets GFPT2 Gene Knockout Cell Lines apart from other genetic models is their precise genomic editing, which ensures complete and specific gene disruption, minimizing off-target effects. Additionally, their versatility allows integration into a wide range of experimental designs, making them suitable for cellular, biochemical, and therapeutic studies.
For researchers and clinicians alike, GFPT2 Gene Knockout Cell Lines provide an indispensable resource that enhances experimental rigor and can lead to significant breakthroughs in understanding cellular metabolism and its implications in human health. Our company prides itself on its expertise in creating high-quality biological products, ensuring that researchers have access to reliable and innovative tools for advancing scientific discovery.
Please note that all services are for research use only. Not intended for any clinical use.
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