Gene: GDAP2
Official Full Name: ganglioside induced differentiation associated protein 2provided by HGNC
Gene Summary: Predicted to act upstream of or within response to retinoic acid. Located in lysosomal membrane. Implicated in autosomal recessive spinocerebellar ataxia 27. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO17417 | GDAP2 Knockout cell line (HeLa) | Human | GDAP2 | 1:3~1:6 | Negative | Online Inquiry |
KO17418 | GDAP2 Knockout cell line (HCT 116) | Human | GDAP2 | 1:2~1:4 | Negative | Online Inquiry |
KO17419 | GDAP2 Knockout cell line (HEK293) | Human | GDAP2 | 1:3~1:6 | Negative | Online Inquiry |
KO17420 | GDAP2 Knockout cell line (A549) | Human | GDAP2 | 1:3~1:4 | Negative | Online Inquiry |
GDAP2 Gene Knockout Cell Lines are advanced biological tools specifically designed to study the function of the GDAP2 gene, a significant player in neural function and mitochondrial dynamics. By employing CRISPR/Cas9 gene-editing technology, these cell lines provide a precise alteration of the gene's expression, allowing researchers to investigate its role in cellular processes, particularly those related to neurodegenerative diseases.
The key function of the GDAP2 gene involves its regulation of mitochondrial morphology and function, contributing to critical cellular energy metabolism and apoptosis pathways. The knockout models enable the assessment of physiological alterations that occur in the absence of GDAP2, facilitating experiments that can elucidate the gene's contribution to synaptic transmission, cellular stress response, and overall neuronal health. This mechanistic understanding is essential for uncovering therapeutic targets in neurodegenerative conditions, such as Charcot-Marie-Tooth disease and other peripheral neuropathies.
Scientifically, the GDAP2 Gene Knockout Cell Lines hold substantial importance in basic and translational research settings, offering a robust platform for drug discovery, gene therapy exploration, and functional genomic studies. Unlike traditional cell models, these knockout lines ensure the specific elimination of the GDAP2 gene, minimizing off-target effects and providing clear insights into gene functions.
One of the standout advantages of our GDAP2 knockout cell lines is their user-friendly accessibility and reliable performance in various applications. Researchers can confidently utilize these lines to conduct in-depth analyses without the complexities and variability often associated with other models. Furthermore, our commitment to quality assurance ensures that each cell line is verified for knockout efficiency and consistency, setting our product apart from competitors.
Research and clinical communities seeking to advance their understanding of neurobiology will find immense value in GDAP2 Gene Knockout Cell Lines. These tools not only aid in uncovering the pathways of gene function but also accelerate the translation of basic research into potential clinical therapies. Our company prides itself on its expertise in providing high-quality biological products that empower scientists to achieve groundbreaking discoveries in their respective fields.
Please note that all services are for research use only. Not intended for any clinical use.
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